Now showing items 15-34 of 51
García-Chica, Jesús (Date of defense: 2023-12-01)
Brain lipid metabolism has a key role in many physiological processes, and its malfunction is associated with a plethora of diseases, such as obesity and glioblastoma multiforme (GBM). Carnitine palmitoyl transferase 1A ...
Merino Gómez, María (Date of defense: 2023-04-21)
The field of tissue engineering relies on the use of biomaterials as scaffolds for tissue and organ regeneration. If properly designed, these scaffolds can mimic the in vivo microenvironment while also providing initial ...
Rodríguez González, Raquel (Date of defense: 2023-02-07)
The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body cannot regenerate large ...
Bru Rullo, Samuel (Date of defense: 2015-07-20)
Throughout its lifespan, eukaryotic cells steadily consume free cytoplasmic orthophosphate to produce phospholipids and mRNA. However, during DNA synthesis, in a matter of minutes, cells require large amount of phosphate ...
Masip Sales, Núria (Date of defense: 2022-01-27)
Fa quasi 40 anys del descobriment de les ciclines, les proteïnes oscil·lants tradicionalment dividies en dos grups, “cicle cel·lular” i “ciclines transcripcionals”, que duen a terme els seus rols juntament amb la seva ...
Pérez - Martín, Hipólito (Date of defense: 2023-11-17)
El tabaquismo es reconocido a nivel global como un factor de riesgo significativo para la salud pública y una de las principales causas de muertes prevenibles. España ha implementado políticas de control del tabaco con el ...
Lidón Moyano, Cristina (Date of defense: 2017-10-06)
In Spain, two smoke-free laws have been passed after the approval of the FCTC. In 2005, it came into effect a smoke-free legislation (Law 28/2005). This law was a great advance for public health in Spain; however, it was ...
Navarro Martínez, Lourdes (Date of defense: 2017-09-29)
Las proteínas TCF7L2 (transcription factor 7-like 2) son un conjunto de factores de transcripción que participan en la vía Wnt y son responsables, entre otras funciones, del mantenimiento de las células madre y la formación ...
Lamarca Dams, Aloa (Date of defense: 2013-09-13)
Peripheral neuropaties are one of the major complications of the Peripheral Nervous System. Depsite the big importance of those pathologies, less drugs are effective for their treatment, and most of the prescribed drugs ...
Díez Deustua, Patricia (Date of defense: 2015-12-02)
En el presente trabajo revisamos las diferentes variables que han sido asociadas al perdón. Son muchos los factores que influyen en que dicho proceso se lleve a cabo o no. Estudios previos han analizado la importancia ...
Pérez Paredes, Alexis E. (Date of defense: 2022-07-22)
The cell cycle is regulated at different layers of control in either homeostatic or non-homeostatic conditions. Hence, in this work we analyse how time and stress modulate the cell cycle through the activity of the G1 ...
Ramírez Flores, Sara (Date of defense: 2014-07-18)
Recent data suggest that ghrelin exerts its orexigenic action through regulation of hypothalamic AMP-activated protein kinase pathway, leading to a decline in malonyl-CoA levels and desinhibition of carnitine palmitoyltransferase ...
Gámiz Sanfeliu, María (Date of defense: 2017-07-11)
Forgiveness is a human strength mainly helpful for the wellbeing of social relationships. Research has showed the potential benefits of forgiving for physical and mental health as well as for restoring relationships. As a ...
Celma Nos, Ferran (Date of defense: 2022-05-17)
Iron is a biometal involved in many physiological processes essential for life. Regulation of both systemic and cellular iron homeostasis is crucial for health. The IRP/IRE post-transcriptional regulatory system is in ...
Sánchez Botet, Abril (Date of defense: 2018-07-18)
El cáncer colorrectal (CRC) es uno de los cánceres más comunes en todo el mundo, con un 8-10% de estos tumores que presentan una mutación BRAF (V600E). Las ciclinas son oncogenes comúnmente desregulados en muchos cánceres, ...
Parellada Insa, Héctor (Date of defense: 2012-07-16)
Para la mayoría de tratamientos dentales, es efectiva la utilización de técnicas anestésicas de tipo infiltrativo, consiguiendo el bloqueo efectivo del estímulo doloroso en todos los dientes de la arcada superior y del ...
Balfagón Martín, Aranzazu (Date of defense: 2013-10-01)
Este trabajo es parte de la investigación del Grupo de investigación de Arquitecturas Genéticas (2009 SGR 862). El objetivo global del grupo es investigar sobre las nuevas formas arquitectónicas y materiales para tratar ...
Giordano, Ana Bárbara (Date of defense: 2021-02-19)
Nowadays, the most common solution to maintain the teeth of patients that have suffered from a traumatism or a profound caries and have ended with root canal infection is to perform a root canal treatment. For this purpose, ...
Díez Tercero, Leire (Date of defense: 2021-06-08)
Bone is a complex and dynamic tissue that fulfills several critical functions such as protecting vital organs including the brain, heart and lungs; providing sites of attachment for muscles to allow movement and maintaining ...
González Marrón, Adrián (Date of defense: 2019-12-16)
Fumar es uno de los principales factores de riesgo evitables de morbimortalidad. Debido a la epidemia de tabaco, la prevalencia de mujeres fumadoras ha aumentado durante las últimas décadas. Entre las causas de mortalidad ...