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From pixels to particles: multi-physics meshless model of the heart
The functioning of the heart, which main role is pumping blood to the rest of the body, is the result of a complex combination of multi-scale physical processes from the molecular to the tissue level. The predominance of ...
From populations to species : Unravelling the unknowns of ageing with two complementary approaches
Ageing is a very complex phenotype that has been widely studied, but is still largely unknown. Most of the studies focus on a single species, or on performing genome wide association studies in human cohorts, but this only ...
From preconcentration to rapid detection of exosomes as biomarkers in clinical diagnosis
En l’actualitat, existeix demanda de biomarcadors per poder millorar la detecció de malalties en una etapa inicial, el seguiment de pacients i dissenyar estratègies terapèutiques. Els exosomes són partícules biològiques ...
From quantum foundations to quantum information protocols and back
Physics has two main ambitions: to predict and to understand. Indeed, physics aims for the prediction of all natural phenomena. Prediction entails modeling the correlation between an action, the input, and what is subsequently ...
From quantum memories to single-site addressing with three-level atoms
El camp de la informació quàntica, que sorgeix de la combinació entre la teoria de la informació i la física quàntica, ha experimentat un enorme progrés durant les darreres dècades, donant lloc a avenços revolucionaris en ...
From Quantum Source Compression to Quantum Thermodynamics
Aquesta tesi aborda problemes en el camp de la teoria de la informació quàntica, específicament, la teoria quàntica de Shannon. La primera part de la tesi comença amb definicions concretes de models de fonts quàntiques ...
From rice fields to seabirds: an integrative approach to study mercury dynamics in the Ebro Delta
Mercury pollution is of great concern for the scientific community due to their ubiquity and persistence in the environment. Its bioaccumulation and biomagnification capacities along food webs enhance their toxicity both ...
From RNA to histological images: linking the transcriptome with human phenotypes through statistical learning
Genomic datasets are fundamental to broaden our understanding of human biology in the context of health and disease. However, the high-dimensional nature of gene expression and other molecular traits poses a challenge when ...
From Romanesque to Gothic: A compositional, morphological and formal study of medieval cultural heritage objects
[eng] The present PhD thesis is focused on the study of the compositional, morphological and formal characteristics of medieval cultural heritage objects, and more specifically manuscripts and champlevé enamels of Limoges, ...
From sequence to structure: determinants of functional and non-functional. Protein aggregation
El estudio de la agregación proteica representa un campo de investigación desafiante que abarca tanto el área biomédica como la biotecnológica. El creciente número de enfermedades humanas asociadas a la acumulación de ...
From simple to complex multicellularity : on the preconditions, design spaces and the evolution of neural agents
Les grans transicions evolutives han transformat profundament la manera com la informació s'organitza i es transmet, a vegades en la forma d'un nou nivell jeràrquic que conté entitats que prèviament es comportaven com ...
From site to inter-site user engagement : fundamentals and applications
L’objetiu d’aquesta tesi és aprofundir en el concepte de participació i compromís dels usuaris en pàgines web i analitzar com mesurar aquesta interacció. Comencem estudiant les mètriques del comportament online, les quals ...
From software as a good to software as a service (SAAS): a methodology to define the transformation towards the SAAS business model
Cloud Computing o computació en el núvol pot ser entesa com a una tecnologia disruptiva. Tanmateix, el cloud computing és sobretot un model de negoci.Empreses proveïdores de software que distribueixen les seves aplicacions ...
From spectrometric data to metabolic networks: an integrated view of cell metabolism
La biologia molecular ha avançat considerablement gràcies a importants progressos com la seqüenciació del ADN o la seva modificació per CRISPR. Tot i això, per entendre el metabolisme requerim estudiar els perfils metabòlics ...
From telegraphic to natural language: an expansion system in a pictogrambased AAC application
En aquesta tesi doctoral, presentem un sistema de compansió que transforma el llenguatge telegràfic (frases formades per paraules de contingut no flexionades), derivat de la comunicació augmentativa i alternativa (CAA) ...
From the clinic to the farm: Applying sequencing and de novo assembly to characterize One-Health bacterial pathogens
Les infeccions causades per bacteris resistents a múltiples antibiòtics son una amenaça tant per a la salut animal com la humana degut a la limitació en el tractament, la qual pot portar a complicacions clíniques severes, ...
From the design to the in vivo evaluation of novel soluble epoxide hydrolase inhibitors
Epoxieicosatrienoic acids acids (EETs) are endogenous chemical mediators derived from arachidonic acid that show anti-inflammatory, antihypertensive, analgesic, angiogenic and antiatherosclerotic effects. Soluble epoxide ...
From the discovery of epistatic events in Type 2 Diabetes Mellitus to the study of related gene expression regulatory variation
[eng] One of the major and most challenging goals of Biomedicine during the last centuries has been the study of the human biological mechanisms, and its relation with traits and diseases. Particularly, in the case of ...
From the effectiveness of the right to housing to the right to the city: a three-dimensional rationality for Brazil and Spain
The conflict between property system and the right to housing has evolved into a more complex inquiry since the beginning of the present research. Our initial analysis on the effectiveness of the social function in ownership ...
From the flake to the blade: the technological evolution of the Middle Paleolithic blade phenomenon
El tecno-complex europeu del Paleolític Mitja mostra grans tendències cronològiques en els canvis de la industria lítica i una diversitat tècnica interna que és difícil d’explicar dins d’un marc homogeni. Aquest treball ...
