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Now showing items 30707-30726 of 42429
Novel lubrication system to improve the excessive wear in wind turbine yaw and pitch gears
Manufacturers of wind turbines have observed a new phenomenon that appears in high power wind turbines: excessive wear in the teeth located at 0º in the pitch bearing. In order to design more efficient wind turbines, ...
Novel markers and targets of collective tumor cell invasion before and after anti-angiogenic therapies
Local invasion is a key cell-biological event in the metastatic cascade. In response to a changing microenvironment, cancer cells may act using two main strategies of invasion: single cell invasion and collective invasion. ...
Novel materials and processes for gate dielectrics on Silicon carbide
There is considerable evidence of the need for a semiconductor technology which exceeds the limitations imposed by silicon across a wide spectrum of industrial applications. Wide bandgap semiconductor, such as silicon ...
Novel mechanisms and transcription factors involved in the control of stomatal behaviour in Arabidopsis thaliana / Nuevos mecanismos y factores de transcripción involucrados en el control del comportamiento estomático en Arabidopsis thaliana
The increase in water use efficiency in order to maintain or improve crop yields in times of global warming and progressive reduction of water resources is one of the major challenges faced by agricultural sciences in the ...
Novel mechanisms of transcriptional regulation by the yeast hog 1 mapk
En la levadura S. cerevisiae, un incremento de la osmolaridad extracelular activa la vía de Hog1, lo que produce una compleja respuesta adaptativa. Entre las respuestas adaptativas que Hog1 coordina, está un importante ...
Novel mechanistic link between microtubule disruption and inhibition of tumor angiogenesis
L'angiogènesis, el desenvolupament de nous vasos sanguinis a partir de vasculatura preexistent, és un procés complex que involucra múltiples productes gènics expressats per diferents tipus cel.lulars, i tots ells contribueixen ...
Novel metal insulator metal capacitors based on electrosprayed colloidal nanoparticles
This work develops a novel capacitor device based on the use of nanotechnology. The device starts from the exiting metal-insulator-metal (MIM) concept, but instead of a continuous insulator layer, dielectric nanoparticles ...
Novel methodologies for the conjugation and cyclisation of polyamides
An alternative allowing diene-derivatised polyamides to be used in Diels-Alder conjugation reactions has been explored and developed. In this methodology, conjugation takes place between a fully protected, resin-linked ...
Novel methods and tools for corneal barrier function assessment through non-invasive impedance measurements
La còrnia és una estructura transparent ubicada a la part frontal de l’ull que permet la transmissió de la llum i protegeix globus ocular d’agressions externes. La principal característica de la còrnia és la seva transparència. ...
Novel methods for multiple sequence alignment and evolutionary modeling
El continuo aumento de los proyectos de producción de datos genómicos a gran escala, como el "Earth BioGenome Project" (Lewin et al., 2018), pone los métodos de análisis de datos bajo una presión sin precedentes. Es necesario ...
Novel methods for plasmonic nanoparticles imaging inside cells using dark-field microscopy
The potential impact of noble metal nanoparticles (NPs) in diverse fields, particularly medicine, is tremendous. However, before NPs can be routinely used in clinical practices, it is fundamental to comprehensively study ...
Novel methods for the detection of exosomes as biomarkers for non-communicable diseases
En aquesta tesi doctoral es presenta el desenvolupament de noves eines per al diagnòstic precoç i el seguiment de malalties no transmissibles. Tot i que existeixen metodologies d’alt rendiment disponibles al mercat per ...
Novel methods for the efficacy and safety in the artificial pancreas intended for domiciliary use
Type 1 diabetes (T1D) is an autoimmune disease that targets the insulin producing β-cells in the pancreas that results in chronically elevated blood glucose (BG) levels and requires lifelong insulin-replacement therapy. ...
Novel Modes of Regulation of Cyclin Dependent Kinase Cdk1
Les quinases dependents de ciclina (CDKs) dirigeixen la progressió del cicle cel·lular a les cèl·lules eucariotes. A l’organisme eucariota model Saccharomyces cerevisiae (llevat de gemmació) una sola quinasa dependent ...
Novel molecular alterations in amyotrophic lateral sclerosis and frontotemporal lobar degeneration spectrum
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are clinically distinct neurodegenerative diseases that are connected by genetic and pathological overlap. ALS patients present with muscle ...
Novel molecular and colloidal catalysts for c-c bond formation processes
Esta tesis doctoral se centró en la síntesis y la caracterización de nanopartículas metálicas (Pd, Ni, Pt) estabilizadas por varios tipos de ligandos y el uso de estas nanopartículas en reacciones de formación de nuevos ...
Novel molecular catalysts for water oxidation: towards artificial photosynthesis
L’objectiud’aquesta tesi és el desenvolupamenticaracteritzacióde nouscatalitzadors per a l’oxidació d’aigua a partir complexos metàl•lics, especialment amb metalls de la primera sèrie de transició. En el segon capítol ...
Novel molecular tools to study mycoplama cells
Els micoplasmes són patògens humans que es caracteritzen per la seva reduïda mida i per ser els organismes de vida lliure coneguts amb els genomes més petits. Tot i la seva aparent simplicitat a nivell genòmic presenten ...
Novel multi-target directed ligands as drug candidates against Alzheimer’s disease
Alzheimer’s disease (AD) is the main neurodegenerative disorder and one of the most important health-care problems worldwide, because of its high prevalence and personal and economic impact. To aggravate this situation, ...
Novel multifunctional biomimetic peptides for bone tissue engineering
(English) Mimicking bone extracellular matrix (ECM) is essential to improve cell-material interactions. In this regard, the functionalization of materials with biomolecules derived from the bone ECM is a promising approach. ...
