Mostrando ítems 8237-8256 de 11297
Soler-Ventura, Ada (Fecha de defensa: 2021-03-05)
L’aplicació de tècniques d’alt rendiment, com la transcriptòmica i la proteòmica, en l’estudi de l’espermatozoide humà, ha permès obtenir grans avenços en la coneixença de la seva composició i funció normal, així com ...
Subirós Funosas, Ramon (Fecha de defensa: 2011-07-21)
Els pèptids són biopolímers naturals amb una importància cabdal en el cos humà, actuant com a neurotransmissors, endorfines o hormones. Recentment, s’han descobert propietats molt interessants de pèptids amb aplicacions ...
Bramon Planas, Dolors (Fecha de defensa: 1998-12-17)
L'any 1922 Josep Ma Millàs i Vallicrosa publicà "Els Textos d'historiadors musulmans referents a la Catalunya Carolíngia" ("Quaderns d'Estudi", Barcelona, XIV, 125-161). Aquest treball constituia una síntesi de la seva ...
Ubals Cazorla, Maria (Fecha de defensa: 2024-05-16)
[cat] INTRODUCCIÓ: Les infeccions de transmissió sexual (ITS) ulceratives, com la sífilis i l’Mpox, són un problema important de salut pública que han experimentat un creixement durant els últims anys. Per fer- hi front ...
Mercadé Frutos, Débora (Fecha de defensa: 2018-12-13)
La tuberculosi és una infecció bacteriana causada per un micobacteri anomenat Mycobacterium tuberculosis. Actualment és la primera causa mundial de mortalitat causada per un agent infecciós fins i tot per sobre de la ...
Tolrà Rovira, Roser (Fecha de defensa: 2017-07-21)
L'objectiu principal d'aquesta Tesi doctoral ha estat l’obtenció d’una via alternativa a les existents per a l'obtenció d'un intermedi clau, 1, en la síntesi d'un fàrmac anticoagulant. La nova via havia de ser novedosa i ...
Motos Galera, Ana (Fecha de defensa: 2022-12-21)
[eng] INTRODUCTION: Nosocomial pneumonia caused by Pseudomonas aeruginosa is associated with high mortality and morbidity. Furthermore, the high incidence of multi-resistance to antimicrobials makes both empirical and ...
Segovia Laserna, Rosario (Fecha de defensa: 2022-03-08)
After decades of exorbitant antibiotic misuse and overuse in human medicine, agriculture and livestock industry, multidrug resistant bacteria (MDR) have become a major medical concern. In this regard, the design of new, ...
Grañé Boladeras, Natàlia (Fecha de defensa: 2012-12-21)
hENT2 is the human nucleoside transporter for which most splice variants have been described to date, in contrast to hENT1 for which no variants have been reported yet. In this dissertation, we have identified 3 novel ...
Sola Lao, Irene (Fecha de defensa: 2016-11-15)
This PhD Thesis pursues the development of novel anti-Alzheimer and antiprotozoal drug candidates upon exploitation of three different novel approaches: Multitarget therapies, Drug repurposing, and Validation of a novel ...
Gandioso Ubieto, Albert (Fecha de defensa: 2018-11-12)
In the present Thesis, it has been carried out the development of new chemical tools for the diagnosis and treatment of cancer through the use of light as an external factor. On the one hand, light can be used to control, ...
Postma, Tobias Maria (Fecha de defensa: 2014-03-21)
Cysteine (Cys) is a unique amino acid due to its ability to form reversible covalent disulfide bonds. These bonds cause conformational constraints which make peptides or proteins more rigid and stable. In addition, the ...
Fabregas Vallvé, Norma (Fecha de defensa: 2013-09-20)
The general objective of this PhD thesis is to investigate the mechanistic bases for plant hormones Brassinosteroids (BRs) action in plant vascular development. To this end, we have used a multidisciplinary approach by ...
Lluscà Jané, Marta (Fecha de defensa: 2015-07-10)
The objective of this work was to study two different light management approaches to enhance the efficiency of thin film Si solar cells and these were the manipulation of the light path (light trapping) and changing the ...
Infanzón Ramos, Belén (Fecha de defensa: 2017-09-15)
This thesis is focused in the identification and improvement of lipases for biotechnological application. The importance of lipases is increasing in several industries. However, the commercial use of lipases is still a ...
Sallaberry Pinto, Júlia (Fecha de defensa: 2019-03-22)
Local invasion is a key cell-biological event in the metastatic cascade. In response to a changing microenvironment, cancer cells may act using two main strategies of invasion: single cell invasion and collective invasion. ...
Legnaioli, Tommaso (Fecha de defensa: 2013-02-26)
The increase in water use efficiency in order to maintain or improve crop yields in times of global warming and progressive reduction of water resources is one of the major challenges faced by agricultural sciences in the ...
Brun Cubero, Omar (Fecha de defensa: 2016-07-27)
An alternative allowing diene-derivatised polyamides to be used in Diels-Alder conjugation reactions has been explored and developed. In this methodology, conjugation takes place between a fully protected, resin-linked ...
Andrés Benito, Pol (Fecha de defensa: 2019-12-17)
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are clinically distinct neurodegenerative diseases that are connected by genetic and pathological overlap. ALS patients present with muscle ...
Pérez Areales, Francisco Javier (Fecha de defensa: 2017-07-14)
Alzheimer’s disease (AD) is the main neurodegenerative disorder and one of the most important health-care problems worldwide, because of its high prevalence and personal and economic impact. To aggravate this situation, ...