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  2. Universitat de Barcelona
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Heteromerización de receptores de adenosina A2A, dopamina D2 y cannabinoides CB1. Implicaciones farmacológicas y funcionales. 

Carriba Domínguez, Paulina (Date of defense: 2007-04-26)

La visión de los receptores acoplados a proteína G ha evolucionado en los últimos años. Clásicamente se consideraban unidades individuales capaces de producir una señal intracelular; actualmente, está ...

The first 3D structural model of an eukaryotic heteromeric aminoacid transporter / Primer model estructural en 3D d’ un transportador heteromèric d’aminoàcids eucariota 

Costa i Torres, Meritxell (Date of defense: 2012-05-04)

Introduction Heteromeric amino acid transporters (HATs) are composed of a heavy subunit (rBAT or 4F2hc) and a light subunit (b0 + AT, ASC1, LAT1, LAT2, y + LAT1, y + LAT2 and xCT), joined by a disulfide ...

Characterization of endothelial cell metabolism under different microenvironmental challenges: exploring therapeutic implications of targeting glycogen degradation 

Jayaraman, Anusha (Date of defense: 2016-07-05)

Angiogenesis is the formation of blood vessels from the pre-existing ones and is required for distributing nutrients and oxygen to the tissues through the blood flow. This process is important for tumour ...

Implicacions fisiopatològiques de l'alteració del transportador concentratiu de nucleòsids hCNT1 

Mata i Ventosa, Aida (Date of defense: 2019-11-29)

L’entrada de nucleòsids a la cèl·lula està regulada pels transportadors concentratius de nucleòsids (hCNTs, família gènica SLC28) i transportadors equilibratius de nucleòsids (hENTs, família gènica ...

Funciones in vivo del regulador transcripcional HNF1a (MODY3) 

Fernández de Luco Hernández, Reina (Date of defense: 2007-01-22)

Las mutaciones en el factor de transcripción HNF1a son la causa más frecuente de diabetes tipo MODY. HNF1a está implicado en una compleja red transcripcional responsable de la diferenciación y función ...

Study of the Electron-Transfer properties of phenolics and their relationship with the biological activity on cancer cells 

Carreras Cardona, Anna (Date of defense: 2012-05-04)

During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical ...

Proteïnes que estructuren i remodelen la cromatina espermàtica. Alguns casos especials 

Giménez Bonafé, Pepita (Date of defense: 1999-11-05)

La major part del treball està enfocat en l'estudi de les proteïnes nuclears bàsiques espermàtiques, també anomenades protamines.<br/><br/>Les protamines són proteïnes que tenen la funció de compactar ...

Heterómeros de receptores de dopamina. Nuevos mecanismos para la regulación de la transmisión dopaminérgica 

Moreno Guillén, Estefanía (Date of defense: 2012-04-25)

El Objetivo General de esta Tesis ha sido investigar la formación y función de heterómeros entre receptores de dopamina y otros receptores que puedan estar implicados en la regulación de la transmisión ...

Role of DOR/TP53INP2 in the control of muscle protein degradation = Papel de DOR/TP53INP2 en el control de la degradación de proteínas en el músculo esquelético 

Martinez Cristobal, Paula (Date of defense: 2016-12-01)

Protein homeostasis (proteostasis) results from the fine regulation of synthesis and degradation. The nuclear cofactor DOR/TP53INP2 was identified originally as a protein expressed in PML of nuclear ...

Structural studies of Heteromeric Amino acid Transporters (HATs): Validation of the first 3D structural model of a HAT (human 4F2hc/LAT2) and identification of new HAT targets for 3D‐crystallization 

Álvarez Marimón, Mª Elena (Date of defense: 2014-10-27)

Heteromeric amino acid transporters (HATs) mediate the transport of amino acids through the plasma membrane. They are composed of two subunits (a heavy and a light one) linked by a conserved disulfide ...

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Palacín Prieto, Manuel (10)

Cascante i Serratosa, Marta (9)

Franco Fernández, Rafael (9)

Pastor Anglada, Marçal (9)

Villarroya i Gombau, Francesc (9)

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Date of defense

2020 - 2024 (2)

2010 - 2019 (82)

2000 - 2009 (54)

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Catalan (63)

Spanish (43)

English (35)

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Ciències Experimentals i Matemàtiques (143)

Metabolisme (12)

Proteïnes (11)

Oncologia (10)

Càncer (9)

... Show more

Subjects

577 (145)

58 - Botany (2)

615 - Pharmacology. Therapeutics. Toxicology. Radiology (2)

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Open access (145)

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