Now showing items 1349-1368 of 3232
Tapial Rodríguez, Javier (Date of defense: 2018-12-14)
Alternative splicing (AS) is a post-transcriptional mechanism for gene expression regulation affecting almost every multiexonic gene in mammals. However, the impact of AS at the proteomic level remains under debate. In ...
Hoffmann, Tobias (Date of defense: 2021-04-08)
The splicing regulatory protein RBM10 is frequently mutated in bladder carcinomas. Analysis of RNA sequencing data of 476 bladder tumours (UROMOL) identified 469 alternative splicing (AS) events associated with RBM10 ...
Ertl, Iris Elisabeth (Date of defense: 2015-02-20)
El complexos SWI/SNF són remodeladors de cromatina dependents d’ATP que es troben altament conservats al llarg de l’evolució. Aquests complexos poden regular l’accessibilitat a una zona genòmica alterant l’estat de la ...
Rojas Salas, Jose Manuel (Date of defense: 2022-07-05)
En esta investigación doctoral se estudian los fundamentos y límites de la responsabilidad jurídico-penal del jefe o superior jerárquico de organizaciones delictivas por los delitos cometidos por sus subordinados. En ...
Andrade Moreno, Marcos Antonio (Date of defense: 2017-07-12)
The purpose of this research is to elucidate the philosophical foundations of the Margin of Appreciation Doctrine of the European Court of Human Rights. For this, two basic problems are distinguished: the conceptual problem ...
Montiel Fernández, Juan Pablo (Date of defense: 2008-09-20)
Una adecuada interpretación del principio de legalidad ofrece buenas razones para admitir la analogía in bonam partem en el Derecho penal aunque de un modo limitado. Incluso cuando el juez mediante ésta excluye o limita ...
Garin Boronat, Manuel (Date of defense: 2012-05-29)
Esta tesis estudia el gag visual en tanto que imagen en movimiento, analizando sus formas, modelos y funciones esenciales. Se parte de una serie de ejemplos clave del cine mudo y el slapstick para rastrear su evolución ...
Inostroza, Maria Victoria (Date of defense: 2021-09-27)
The focus of this dissertation is the globalized world of today. As a complex phenomenon, globalization has many and varied effects on our lives. Some of them are paradigmatically negative such as the impact on individual ...
Martín Albà, Sonia (Date of defense: 2001-06-28)
El cuerpo principal de esta memoria de tesis doctoral se centra en las diferencias contables y fiscales en la regulación de los gastos fiscalmente deducibles en este Impuesto y, especialmente, de las amortizaciones y ...
Vorobyeva, Tamara (Date of defense: 2020-11-24)
Previous research has demonstrated the difficulty of the grammatical gender category for L2 learners and bilingual speakers. The main goal of this study is to investigate the gender agreement by 30 young L1 heritage speakers ...
Lamarca Casado, Rosa (Date of defense: 2006-06-11)
Aquesta tesi avalua l'existència de diferencies per gènere en la relació entre discapacitat i mortalitat, i aspectes metodològics en l'anàlisi de supervivènciad'estudis de gent gran. Es van utilitzar les dades provinents ...
Campos-Serna, Javier (Date of defense: 2014-01-13)
Esta tesis doctoral está basada en la identificación de las desigualdades de género en salud laboral descritas en la literatura científica, así como en el análisis de las desigualdades de género en la población ocupada en ...
Borao Arriazu, Sonia (Date of defense: 2022-07-22)
Schizosaccharomyces pombe initiates sexual development under nitrogen starvation, changing the transcription patterns of many genes to allow sexual differentiation. MBF transcription factor recognize specific sequences ...
Breschi, Alessandra (Date of defense: 2016-11-28)
Mice are the premier model organisms to study human biology and disease, but there is still debate about the extent to which molecular mechanisms are conserved between human and mouse. With the advance of next-generation ...
Colombaro, Ivano (Date of defense: 2022-06-17)
This doctoral thesis aims to find a connection between two different disciplines. On the one hand, the electromagnetic theory, one of the most known and most applied theories in physics, properly described by the famous ...
Xiao, Ping (Date of defense: 2014-07-08)
Behind every good advertisement there is a creative concept, a Big Idea. In contrast to the countless number of ads, a small number of patterns of effective communication (idea templates) have been uncovered, which are ...
Marco Giménez, Andrés (Date of defense: 2022-03-14)
Our current knowledge about the function of human genes is mostly based on data from genetic studies using animal models. However, divergence among species may hamper the understanding of genetic mechanisms underlying ...
Sánchez Danés, Adriana (Date of defense: 2012-05-21)
Parkinson’s disease (PD) is an incurable, chronically progressive neurodegenerative disease leading to premature invalidity and death. The locomotor disability of PD patients is mainly rooted in the gradual and insidious ...
Mathews, Zenon (Date of defense: 2011-01-12)
Es considera que la cognició biològica fa servir mecanismes com la predicció, l'anticipació i l'atenció per resoldre tasques complexes. S'ha suggerit que aquests mecanismes es materialitzen en els mamífers a través ...
Berniell Lee, Gemma (Date of defense: 2010-07-19)
La presente tesis, titulada “Genes, peoples and languages in Central Africa”, examina los patrones de diversidad genética en poblaciones del oeste de Africa central, más específicamente, poblaciones Bantús y Pigmeas de ...