Universitat Pompeu Fabra
Now showing items 21-40 of 48
L'asma és una malaltia d'etiologia complexa, formada per factors genètics i ambientals, on la interrelació de ambdós factors mitjançant interaccions gen-ambient juga un paper clau. L'objectiu d'aquesta tesi ha sigut ...
El cáncer de pulmón es la forma más mortal de cáncer en el mundo. Recientemente, el estudio del perfil genómico a larga escala de tumores humanos ha impulsado el desarrollo de drogas que tienen como diana terapéutica genes ...
Aquesta tesi doctoral consisteix en una sèrie de deu articles (8 publicats y 2 en premsa) basats en dades recollides a l'estudi AMICS (Asthma Multicentre Infant Cohort Study), portat a terme a Ashford (UK) a Barcelona y a ...
La Enfermedad Pulmonar Obstructiva crónica (EPOC) presenta afectación pulmonar y sistémica y periodos de exacerbación (AEPOC), que contribuyen a su progresión. En algunas ocasiones la AEPOC está causada por microorganismos ...
El déficit de hierro (DH) podría jugar un papel en la enfermedad pulmonar obstructiva crónica (EPOC) dado que es fundamental en la bioenergética celular. Estudio 1: Se analizaron 18 pacientes EPOC con DH y 18 pacientes ...
The general aim of this doctoral thesis was to examine the impact on persons with persistent asthma of inhaled treatment use and sociodemographic factors, in terms of patient-reported outcomes. To achieve this, a new ...
INTRODUCTION: Respiratory muscle weakness and fatigue are related to clinical deterioration in patients with Chronic Obstructive Pulmonary Disease (COPD). Respiratory muscle training (RMT) is a key therapeutic strategy in ...
La neteja del moc i dels patògens dels pulmons, i el transport de gàmets i embrions en els òrgans reproductius de les femelles són funcions clau en els epitelis ciliats, tals com aquells que es troben presents en les vies ...
Background and objectives: Recent research has shown an association between a healthy diet and reduced chronic obstructive pulmonary disease (COPD) incidence. However, the potential role of diet in COPD prognosis is ...
Chronic respiratory diseases, especially chronic obstructive pulmonary disease (COPD), and several molecular mechanisms may predispose to lung cancer (LC) development. Hypothesis: We hypothesized that different biological ...
La caquexia afecta negativamente a los pacientes con enfermedades crónicas y sobre todo en el cáncer. Las estrategias terapéuticas son aún limitadas. Los beta2-agonistas (formoterol) y el soporte nutricional (L-carnitina) ...
Small cell lung carcinoma (SCLC) is a highly lethal disease due to its chemorefractory nature after first line treatment. The mechanisms to overcome this resistance have remained elusive to tackle up to date. MET is a ...
Cachexia and muscle deconditioning, which are the major comorbidities in patients with chronic diseases including lung cancer (LC), impair disease prognosis. Several biological mechanisms are involved in these two muscle ...
Muscle dysfunction and muscle wasting are major systemic manifestations of chronic conditions such as Chronic Obstructive Pulmonary Disease (COPD) and cancer. Several biological mechanisms contribute to such a dysfunction. ...
The general aim of the thesis was to assess the role of nutritional factors in asthma in the French E3N study. The first objective was to compare principal component (PCA) with confirmatory factor analysis (CFA) to identify ...
El objetivo del estudio era identificar las exposiciones ocupacionales relacionadas con asma en empleadas de limpieza doméstica. Un estudio poblacional transversal realizado en 4,521 mujeres mostró que las empleadas del ...
Physical inactivity is a hallmark of Chronic Obstructive Pulmonary Disease (COPD), which relates to outcomes relevant for patients and healthcare providers. Despite its importance, no patient reported outcome (PRO) instrument ...
Respiratory muscle dysfunction is a clinical condition that may be present in both respiratory and non-respiratory diseases. This impairment of muscle function can have a negative effect on clinical outcomes, contributing ...
La rinitis tiene un impacto importante en la salud pública, sin embargo en los adultos no existe una estandarización de la definición en los estudios epidemiológicos. Además, apenas se conocen los factores ambientales de ...
Secondhand smoke (SHS) exposure causes death, disease, and disability among children and non-smoking adults. Total smoking bans have proven effective in preventing and reducing indoor SHS exposures. However, little is known ...
