Ara mostrant els elements 11-20 de 52
Martínez Ara, Guillermo (Data de defensa: 2022-09-19)
During embryonic development, cellular forces synchronize in space and time to generate functional tissue shapes. Apical constriction is a force-generating process necessary to provoke the folding of ...
Cuenca-Ardura, Mirabai (Data de defensa: 2024-01-19)
HNF1A encodes a key transcription factor in insulin-secreting beta cells from pancreatic islets. Heterozygous mutations in HNF1A cause monogenic diabetes, and hypomorphic variants in HNF1A increase ...
Galán i Palma, Luis (Data de defensa: 2023-03-22)
Pluripotent stem cells (PSCs) have the ability to self-renew and give rise to almost every somatic cell type. Because of their enormous potential as a tool for regenerative medicine, understanding ...
Belmonte Mateos, Carla (Data de defensa: 2022-02-03)
Precise regulation of neurogenesis is achieved by differentially allocating the neurogenic competence along the tissue. In the hindbrain proneural gene expression is stereotypically confined in segment ...
Laguillo Diego, Alejandra (Data de defensa: 2021-03-12)
During cell division, microtubules (MTs) organize into a bipolar spindle that drives faithful chromosome segregation through the kinetochore fibers (k-fibers), bundles of parallel MTs that attach the ...
Tolosa Ramon, Queralt (Data de defensa: 2023-07-26)
The outer epithelial layer is the first cell type that emerges during development, providing essential mechanical protection and is indispensable for morphogenesis. Here, we study how the interplay ...
Engel-Pizcueta, Carolyn (Data de defensa: 2023-04-28)
The generation of cell diversity in the embryonic brain relies on the balance between cell proliferation and differentiation. The hindbrain boundary cells specify at the interface between adjacent ...
Kozyczkowska, Aleksandra (Data de defensa: 2022-03-11)
To address one of the most fascinating questions in the history of life, the origin of animal multicellularity, we needed experimentally tractable representatives from each of the unicellular lineages, ...
Plana Carmona, Marcos (Data de defensa: 2021-03-17)
Continuous C/EBPa expression converts B cells into macrophages while its transient upregulation before the Yamanaka factors yields highly efficient iPSC reprogramming. C/EBP members regulate Il6 ...
Traveset Martínez, Laia (Data de defensa: 2020-10-30)
Maintenance of steady-state and stress-adapted hematopoiesis depends on the fitness of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow. Hematopoietic stem cells (HSCs) can adapt to ...