Mostrando ítems 91-100 de 252
Massoni Badosa, Ramon (Fecha de defensa: 2023-03-13)
Specialization and plasticity are hallmarks of immune cells. Thus, charting their heterogeneity is crucial to understand their function and role in diseases. In this setting, single-cell RNA-sequencing ...
Biagini, Simone Andrea (Fecha de defensa: 2019-07-17)
This work explores the genetic landscape of the Western Mediterranean basin. Genome-wide data have been used in order to describe the genetics of the Island of Ibiza and France. In the first case, we ...
González-Vallinas Rostes, Juan (Fecha de defensa: 2013-09-09)
High Throughput Sequencing technologies (HTS) are becoming the standard in genomic regulation analysis. During my thesis I developed software for the analysis of HTS data. Through collaborations with ...
Borsari, Beatrice (Fecha de defensa: 2021-03-26)
We have monitored the transcriptome and the epigenome of human pre-B cells transdifferentiating into macrophages. Analysis of these data provides a general framework to understand the relationship between ...
Melé Messeguer, Marta (Fecha de defensa: 2011-03-29)
En aquest treball es pretén utilitzar la informació que deixa la recombinació al nostres genomes per fer inferències sobre la història evolutiva recent de les poblacions humanes. Per fer-ho, s’ha ...
Chatzou, Maria (Fecha de defensa: 2016-11-07)
One of the main and most recent challenges of modern biology is to keep-up with growing amount of biological data coming from next generation sequencing technologies. Keeping up with the growing volumes ...
Tarruell Pellegrin, Antonio (Fecha de defensa: 2019-06-26)
In female mammals, one of the X chromosomes is epigenetically inactivated through X chromosome Inactivation (XCI) during the epiblast differentiation. However, XCI is later specifically reversed in ...
Sánchez Arroyo, Alicia (Fecha de defensa: 2019-07-03)
One of the main evolutionary transitions is the origin of animal and fungal multicellularity from single-cell ancestors. To address this change, it is necessary to study the extant unicellular relatives ...
Mitsi, Konstantina (Fecha de defensa: 2021-05-28)
Los organismos eucariotas abarcan una diversidad inmensa de formas, tamaños y estilos de vida. Sin embargo, abordar la verdadera amplitud de esa diversidad es una tarea laboriosa. Durante las últimas ...
Colì, Caterina (Fecha de defensa: 2019-11-25)
Alternative splicing (AS) is an important step in the pathway of gene expression and regulation. The splicing process is catalyzed by the Spliceosome, a complex molecular machinery that is dynamically ...