Mostrando ítems 261-270 de 295
Pant, Devesh Chandra (Fecha de defensa: 2018-10-05)
In spite of recent advances in understanding the genetic bases of leukodystrophies, a large number of clinical cases remain unexplained, suggesting that many leukodystrophy-associated genes have yet to ...
Fontseré Alemany, Clàudia (Fecha de defensa: 2020-12-17)
Wild chimpanzee populations are considered to be under threat of extinction due to the damaging consequences of human impact into their natural habitat and illegal trade. Conservation genomics is an ...
Rodríguez Pérez, Juan Antonio (Fecha de defensa: 2017-01-24)
Old age comes coupled with frailty and disease and, thus, the ageing of the World’s population have spurred the interest on the causes and mechanisms of senescence. Senescence has long been a mystery, ...
Ferrando-Bernal, Manuel (Fecha de defensa: 2021-07-09)
The aim of this thesis is to apply Identity by Descent (IBD) methodology to identify ancestry connections among individuals from genetically similar populations. Recombination events diminish the ...
Shaw, Daniel (Fecha de defensa: 2019-12-13)
Understanding what constitutes a true Minimal Cell is a key challenge in synthetic biology. In this work, we present two new tools to aid in this endeavour. i) A novel methodology for minimising the ...
Hernandez Alias, Xavier (Fecha de defensa: 2023-02-23)
Malgrat teixits diferents presenten diferències en l'ús de codons i en els repertoris d'anticodons dels ARNt, el coneixement sobre la co-adaptació entre codó-anticodó en eucariotes multicel·lulars és ...
Ledda, Alice (Fecha de defensa: 2011-05-06)
Els microsat el lits s on seq u encies d'ADN formades per repeticions en t andem de motius curts. Les curtes seq u encies repetides en t andem s on ubiq ues en els genomes dels eucariotes, tant en les ...
Renom, Pere (Fecha de defensa: 2023-02-22)
According to estimates, over the 3.5 billion years that have elapsed since the appearance of life, the Earth has been inhabited by some 4 billion different species, of which 99.99% have already become ...
Lucas, Morghan C. (Fecha de defensa: 2023-04-24)
The aim of this thesis is to delve into sperm RNA dynamics during maturation and paternal inheritance. To obtain an integrative multi-omics view of sperm RNA during these processes, I turned to the new ...
Dall'Olio, Giovanni Marco (Fecha de defensa: 2013-10-28)
In this thesis we developed two approaches to study positive selection and genetic adaptation in the human genome. Both approaches are based on applications of network theory. In the first approach, ...