Guerra Badell, Joana (Date of defense: 2016-10-13)
Adult skeletal muscle has a remarkable capacity of self-repairing after damage. The cellular communication processes and mediator molecules in the regenerative microenvironment that control muscle stem ...
Gonzàlez Busqué, Núria (Date of defense: 2017-09-18)
Snail1 transcription factor is the key inducer of epithelial-to-mesenchymal transition (EMT). Here, we describe a novel role for Snail1 on the regulation of telomere integrity and transcription as well ...
Missarova, Alsu (Date of defense: 2018-04-09)
Isogenic cells exhibit a large degree of cell-to-cell heterogeneity in proliferation, with a subpopulation of cells growing at a substantially lower rate. We conducted a high throughput microscopy screen ...
Pardo Pastor, Carlos (Date of defense: 2018-01-24)
The mechanical dependence of transformation and metastasis is an emerging field, but the role of mechanosensitive channels has been largely omitted. This thesis focuses on the roles played by the ...
Rodríguez Pizà, Ignasi (Date of defense: 2010-07-05)
Les cèl·lules mare embrionàries humanes (hESC) i més recentment les cèl·lules de pluripotència induïda (iPSC) representen una oportunitat sense precedents per al desenvolupament de noves estratègies ...
Masgrau Fortuny, Aina (Date of defense: 2014-09-05)
Cell growth and division requires delivery of new membrane and remodelling factors to the cell surface. In budding yeast, this involves actin-dependent transport of secretory vesicles to sites of ...
Ruiz Roig, Clàudia (Date of defense: 2011-12-02)
A Saccharomyces cerevisiae, un increment de la temperatura comporta diversos efectes deleteris en l’organització interna de la cèl∙lula i indueix una inducció ràpida, massiva i transitòria d’expressió ...
Wibowo, Indra (Date of defense: 2011-07-04)
The purpose of this thesis is to introduce and demonstrate several biological processes or phenomena using posterior lateral line system of zebrafish as a model. The first part of this work focuses on ...
Salat Canela, Clàudia (Date of defense: 2020-09-30)
Living organisms must respond to changes in their environment in order to overcome stress situations. In Schizosaccharomyces pombe, Sty1 MAP kinase is required to survive to a wide range of environmental ...
Pupuleku, Aldi (Date of defense: 2017-11-10)
Human cytomegalovirus (HCMV) infection induces a persistent reconfiguration of the NK cell compartment in some individuals, promoting the development of a mature NK cell subset, hallmarked by high ...