Mostrando ítems 71-80 de 176
Grippa, Alexandra (Fecha de defensa: 2015-06-12)
Most cells store energy in lipid droplets (LDs), specialized storage organelles composed of a neutral lipid core that, during their biogenesis, is packaged into a single phospholipid monolayer decorated ...
Plana Carmona, Marcos (Fecha de defensa: 2021-03-17)
Continuous C/EBPa expression converts B cells into macrophages while its transient upregulation before the Yamanaka factors yields highly efficient iPSC reprogramming. C/EBP members regulate Il6 ...
Khan, Abdul Kareem (Fecha de defensa: 2009-03-05)
La preorganització electrostàtica del centre actiu s'ha postulat com el mecanisme genèric de l'acció dels enzims. Així, alguns residus "estratègics" es disposarien per catalitzar reaccions interaccionant ...
Pareja Gómez, Josep (Fecha de defensa: 2010-11-22)
Pluripotent cells are unique due to their developmental potential and the possibility to study them is the key step to understand human development. These cells are characterized by their ability to ...
Traveset Martínez, Laia (Fecha de defensa: 2020-10-30)
Maintenance of steady-state and stress-adapted hematopoiesis depends on the fitness of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow. Hematopoietic stem cells (HSCs) can adapt to ...
Isús Díaz, Laura (Fecha de defensa: 2017-02-13)
Since the advent of the genomic era, vast amounts of data from heterogeneous biomedical sources have been generated, revealing an overwhelming complexity and creating a need for new computational tools. ...
Millanes Romero, Alba (Fecha de defensa: 2014-01-21)
Although heterochromatin is enriched with repressive traits, it is actively transcribed, giving rise to large amounts of non-coding RNAs. These transcripts are responsible for the formation and ...
Gentile, Maurizio (Fecha de defensa: 2014-09-19)
The marginal zone (MZ) of the spleen contains an innate-like subset of B cells that mount rapid protective antibody responses to polysaccharides and lipids from bloodborne viruses and bacteria. These ...
Mestre Farràs, Neus (Fecha de defensa: 2021-09-16)
La tesi doctoral aquí presentada busca entendre quin és el paper de les proteïnes d’unió a l’ARN en la progressió tumoral, ja que s’ha demostrat que aquestes proteïnes poden regular aspectes que permeten ...
Severino, Jacqueline (Fecha de defensa: 2021-03-30)
X chromosome reactivation in female mouse germ cells is essential for the transmission of one active X chromosome to the progeny. However, despite its key role in development, the mechanistic details and ...