Romão, Daniela (Date of defense: 2021-09-10)
Alterations in developmental transitions are common among animals to compensate for growth disturbances. These variations are usually a consequence of altered steroidal hormone production resulting in ...
Selfa Aspiroz, Idoia Lucía (Date of defense: 2022-02-01)
During the last years, the development of procedures to direct the differentiation of human pluripotent stem cells (hPSCs) towards different renal cell types has resulted in the establishment of approaches ...
Tejedor Vaquero, Sonia (Date of defense: 2018-03-16)
Glucose is a key nutrient for T cells. Despite that T cell activation is impaired when they are deprived of glucose, it has also been shown that T effector responses can be elicited in vivo in glucose-poor ...
Mòdol Cano, Aitor (Date of defense: 2021-04-29)
El cilio primario es una estructura formada por microtúbulos que sobresale de la superficie celular durante G0 teniendo una función de orgánulo sensor. La importancia del cilio es patente por las ...
Di Stefano, Bruno (Date of defense: 2014-06-05)
One of the major goals of current stem cell research is understanding the mechanism of somatic cell reprogramming by Oct4, Sox2, Klf4 and Myc (OSKM) into induced pluripotent stem cells (iPSCs). However, ...
Mestres Gonzalvo, Enric (Date of defense: 2022-02-18)
The embryo culture system is composed by all those elements with the potential to impact embryo development. Its optimization is required to stabilize in vitro embryo culture and produce reliable and ...
Ferreira, Vanessa Miriam dos Reis (Date of defense: 2010-11-22)
Xkid is a Xenopus chromokinesin required for metaphase chromosome alignment and for meiosis I to meiosis II transition in oocytes. The aim of this work was to study the regulation of Xkid by phosphorylation ...
Brckalo, Tamara (Date of defense: 2011-01-24)
The focus of this work was to functionally characterize the CD300e receptor expressed in human monocytes and myeloid dendritic cells and investigate the implications that receptor engagement has on their ...
Sinigaglia, Barbara (Date of defense: 2022-11-25)
Several rainforest hunter-gatherer groups in south-east Asia are characterized by specific morphological features including a particularly dark skin color (D), an extremely short stature (S), the ...
Guha, Sanjib Kumar (Date of defense: 2015-12-18)
X-linked adrenoleukodystrophy (X-ALD) is an inherited neurodegenerative disorder. The genetic bases for all its different phenotypic variants are mutation in the gene encoding the peroxisomal ATP-binding ...