Mostrando ítems 1-10 de 151
Serra Bardenys, Gemma (Fecha de defensa: 2019-12-12)
Oxidation of histone H3 (H3K4ox) by lysyl oxidase-like 2 (LOXL2) is important in triple-negative breast cancer (TNBC) cells to generate compacted heterochromatin regions. However, the molecular mechanisms ...
Buch Mundó, Ignasi (Fecha de defensa: 2012-06-29)
Investigation of protein-ligand interactions has been a long-standing application for molecular dynamics (MD) simulations given its importance to drug design. However, relevant timescales for biomolecular ...
Torrens Fontanals, Mariona (Fecha de defensa: 2022-02-11)
Molecular dynamics (MD) simulations are a well-established technique to characterize the structural motions of biological systems at atomic resolution. However, accessing, viewing, and sharing MD ...
López García de Lomana, Adrián (Fecha de defensa: 2010-10-19)
Els mecanismes de regulaci o de les c el lules poden ser modelats per controlar i entendre la biologia cel lular. Diferents nivells d'abstracci o s'utilitzen per descriure els processos biol ogics. ...
Garriga Nogales, Edgar (Fecha de defensa: 2022-02-15)
In these days of significant changes and the rapid evolution of technology, the amount of datascience has to deal with the growth incredibly fast, and the size of data could be prohibitive.Multiple ...
Moreno Lama, Lucía (Fecha de defensa: 2020-01-16)
Los inhibidores de PARP han surgido como nuevas terapias basadas en el papel essencial de las Poly (ADP-ribosa) polimerasas PARP-1 y PARP-2 en la respuesta a daño en el DNA, explotando el efecto de las ...
Sansó Martínez, Miriam (Fecha de defensa: 2010-07-02)
In Schizosaccharomyces pombe, the MAPK pathway Sty1 is activated upon several stress situations, like osmotic and oxidative stress, stationary phase, UV radiation or heat shock. Since the modulation ...
Castells García, Àlvaro (Fecha de defensa: 2019-07-01)
Chromatin organization and gene expression are interdependent. Previously, our group showed that nucleosomes form groups, termed clutches, whose size correlates with cell state. In this thesis, we ...
Martínez Barriocanal, Agueda (Fecha de defensa: 2009-04-16)
En los últimos años hemos sido testigos de la identificación de múltiples familias de receptores inmunológicos. En este contexto encontramos la recientemente descrita familia IREM/CD300 localizada en ...
Sumi, Angughali Aheto (Fecha de defensa: 2017-01-13)
Epithelial tissues undergo extensive remodeling during embryonic development. Recent studies have revealed that, in a number of developmental processes, epithelial remodeling is associated with pulsations ...