Canal de Torres, Berta (Date of defense: 2018-02-16)
In response to multiple internal and external stresses, yeast cells activate a common transcriptional response known as the Environmental Stress Response (ESR), which can be problematic in S phase, when ...
Maseres Javaloy, Pedro (Date of defense: 2018-03-12)
The p38 mitogen activated protein kinase (MAPK) has a crucial role in cells’ stress adaptation and survival. It also plays a role in physiological processes such as differentiation of skeletal muscle ...
Casadomé Burriel, Laura (Date of defense: 2005-03-01)
Yeast cells are exposed to a wide variety of environment stresses, among them changes in the osmotic conditions. An osmolar upshift leads to fast loose of intracellular water, so living cells have ...
Carbonell Núñez, Caterina (Date of defense: 2016-12-19)
Cells have the ability to respond and adapt to environmental changes through activation of stress-activated protein kinases (SAPKs). Activation of the p38 SAPK is critical to elicit the early gene ...
Noriega Esteban, Núria (Date of defense: 2009-02-27)
La adaptación de la levadura Saccharomyces cerevisiae a condiciones de alta osmolaridad está mediada por la vía de HOG ((high-osmolarity glycerol). La activación de esta vía induce una serie de respuestas ...
Conde Pueyo, Núria (Date of defense: 2014-09-18)
Ongoing efforts within synthetic biology have been directed towards the building of artificial computational devices using engineered biological units as basic building blocks. Such efforts, are limited ...
Caballero de la Torre, María (Date of defense: 2021-09-09)
Retinoblastoma protein (RB) is a negative regulator of the cell cycle. In response to environmental stress, p38 MAPK phosphorylates RB in the N-terminal region, increasing the affinity of RB for E2F, ...
Mas Martín, Glòria (Date of defense: 2007-07-20)
En la levadura S. cerevisiae, un incremento de la osmolaridad extracelular activa la vía de Hog1, lo que produce una compleja respuesta adaptativa. Entre las respuestas adaptativas que Hog1 coordina, ...
Ferreiro Neira, Isabel (Date of defense: 2011-10-07)
Regulation of transcription by Stress Activated Protein Kinases (SAPKs) is an essential aspect for adaptation to extracellular stimuli. In mammals, the activation of the p38 SAPK results in the regulation ...
Zapater Enrique, Meritxell (Date of defense: 2006-12-01)
En el llevat Saccharomyces cerevisiae els canvis en les condicions osmòtiques del medi extracel.lular són sensades per la MAP cinasa Hog1, la qual permet dur a terme l'adaptació cel.lular mitjançant la ...