Mostrando ítems 11-17 de 17
Vali Pour Jamnani, Mischan (Fecha de defensa: 2022-06-02)
Somatic mutations are an inevitable component of ageing and the most important cause of cancer. The rates and types of somatic mutation vary across individuals, but relatively few inherited influences ...
Bassaganyas Bars, Laia (Fecha de defensa: 2013-09-20)
Over the last ten years, improvements in molecular techniques and the arrival of the next-generation sequencing technologies have revealed a large amount of structural variation (SV) in the human genome. ...
Solís Moruno, Manuel (Fecha de defensa: 2021-09-14)
Autoinflammatory diseases are caused by an antigen independent hyperactivation of inflammatory pathways. The first genetic defect linked to an autoinflammatory disease was described almost 25 years ago ...
Frigola Rissech, Joan (Fecha de defensa: 2020-03-13)
The rate at which mutations accumulate along the genome is not uniform but influenced by factors such as chromatin compactness, replication time or transcription. Most of these factors create mutational ...
Fontseré Alemany, Clàudia (Fecha de defensa: 2020-12-17)
Wild chimpanzee populations are considered to be under threat of extinction due to the damaging consequences of human impact into their natural habitat and illegal trade. Conservation genomics is an ...
Burriel Carranza, Bernat (Fecha de defensa: 2024-02-26)
This thesis provides new insights into the evolution of biodiversity in arid regions by exploring the patterns and drivers of reptile diversity in the Hajar Mountains of Southeastern Arabia. We first ...
Elek, Anamaria (Fecha de defensa: 2024-04-19)
Single-cell genomics methods have revolutionized the study of gene expression and regulation at the cell type level. Generating single-cell atlases for species at key phylogenetic positions of the animal ...