Vicario Orri, Elena (Date of defense: 2017-10-03)
The mechanisms by which amyloid beta (Aβ) causes synaptic dysfunction in Alzheimer’s disease (AD) remain elusive. Aβ is derived by sequential cleavage of the amyloid precursor protein (APP) and released ...
Guix Ràfols, Francesc Xavier (Date of defense: 2009-01-22)
Aquesta tesi demostra que el peroxinitrit produït com a conseqüència del pèptid beta-amiloide (A) contribueix l'augment de la relació A42/A40 que ocorre a la malaltia d'Alzheimer. ...
Calvé Pérez, Pablo (Date of defense: 2022-07-04)
Food addiction is closely associated with eating disorders including obesity and binge eating. However, the neural alterations underlying this disorder have not been yet clarified. We have trained ...
Brugulat Serrat, Anna (Date of defense: 2019-06-21)
White matter hyperintensities (WMH) have been associated with increased risk and progression of Alzheimer’s disease (AD). However, the range to which this association can be extended to AD risk factors ...
Pagès-Portabella, Carlota (Date of defense: 2023-10-19)
La música està present en totes les cultures. Tot i tenir les mateixes habilitats auditives, la manera en la què experimentem la música depèn del context cultural, la música que escoltem en el dia ...
Laguna Tuset, Ariadna (Date of defense: 2008-12-18)
El gen DYRK1A es troba situat en una regió del cromosoma 21 humà que s'ha associat a alteracions en el neurodesenvolupament. Aquest treball mostra com canvis en la dosis gènica de Dyrk1A en el ratolí ...
Gutiérrez Martos, Miriam (Date of defense: 2018-06-08)
Drug addiction and several eating disorders share striking similarities in their behavioural patterns triggered by the presence of neuronal alterations in the brain reward circuit. In this Thesis, we ...
López Sánchez, Marcos (Date of defense: 2018-02-05)
Neurodevelopmental disorders are a group of conditions with impairments of the personal, social, academic or occupational behaviour. Autism spectrum disorder is a neurodevelopmental disorder with a high ...
Touriño Raposo, Clara (Date of defense: 2009-02-17)
La 3,4-metilendioximetamfetamina (MDMA, èxtasi) i el cannabis són dues drogues les quals es consumeixen conjuntament de manera habitual. Malgrat que tots dos compostos presenten propietats reforçant i ...
Ortega Crespo, Mireia (Date of defense: 2018-01-23)
Down syndrome (DS) is the most frequent genetic cause of intellectual disability. It is a multifaceted condition characterized by impairments in cognition, communication, behavior and/or motor skills ...