Rodríguez Galindo, Miguel (Date of defense: 2023-11-13)
Tumor progression is dominated by two evolutionary forces: first mutagenesis, which provides the heritable variability where, secondly, natural selection acts. The main challenge of cancer genomics is ...
Palmada Flores, Marc (Date of defense: 2023-11-27)
Modern biology relies on genomic references to perform analyses in most studies. High-quality de novo genome assemblies are key to having references containing all the genomic content of a species. ...
Platania, Leonardo (Date of defense: 2023-10-11)
The South Pacific is an intriguing region for studying evolutionary biology, presenting an exceptional diversity and complex geological and environmental characteristics. New Caledonia, in particular, ...
Pardo Lorente, Natalia (Date of defense: 2023-10-06)
Subcellular compartmentalisation of metabolic enzymes may elicit specific cellular functions by establishing a unique metabolic environment. Indeed, the nuclear translocation of certain metabolic enzymes ...
Alvarez Estapé, Marina (Date of defense: 2023-04-20)
The field of genomics can be used to help in threatened species conservation by guiding conservation efforts. In this thesis we have studied Cuvier’s gazelles to compare the genetic diversity and ...
Cubas Landaluce, Laura de (Date of defense: 2024-01-19)
Los efectos del H2O2 en la fisiología celular, como oxidante y como señalizador es un campo que aún esta en expansión. Para intentar desvelar como ocurren estos fenómenos, hemos utilizado sondas ...
Caro Consuegra, Rocío (Date of defense: 2023-02-15)
As a result of local selective pressures, genetic adaptation leaves distinct recognisable marks in the genomes of human populations. Several cases of positive natural selection have been described in ...
Oswal, Natasha Nikhil (Date of defense: 2023-06-08)
El envejecimiento implica un aumento de la fragilidad en función del tiempo que resulta en la aceleración de la mortalidad. Para comprender el papel temporal de varias proteínas en el envejecimiento, ...
Castro Arnau, Júlia (Date of defense: 2023-10-23)
The molecular mechanisms regulating sperm differentiation (spermiogenesis) and maturation in fishes are largely unknown. In these oviparous species, the initiation of sperm motility is triggered by the ...
Esteller Cucala, Paula (Date of defense: 2023-04-18)
Changes in the epigenetic regulation of gene expression have important implications for evolution. However, the study of these changes (i) has not been consistently assessed across closely related ...