Lucas, Morghan C. (Date of defense: 2023-04-24)
The aim of this thesis is to delve into sperm RNA dynamics during maturation and paternal inheritance. To obtain an integrative multi-omics view of sperm RNA during these processes, I turned to the new ...
Gamarra Figueroa, Gianni Paolo (Date of defense: 2024-01-26)
Acute myeloid leukemias (AMLs) are a type of cancer where undifferentiated myeloid cells abnormally proliferate. Such phenotype can be caused by the expression of chimeric proteins like PML-RARα and ...
González i Colell, Marc (Date of defense: 2024-02-23)
Engineering biology requires a clear set of rules that ensure design predictability. However, certain biological processes difficult the application of these rules, impairing prediction. In the first ...
Burriel Carranza, Bernat (Date of defense: 2024-02-26)
This thesis provides new insights into the evolution of biodiversity in arid regions by exploring the patterns and drivers of reptile diversity in the Hajar Mountains of Southeastern Arabia. We first ...
Delgado Tejedor, Anna (Date of defense: 2024-03-21)
RNA modifications, collectively known as the ‘epitranscriptome’, play a major role in multiple biological processes, including splicing regulation, gene expression regulation and antibiotic resistance. ...
San José Plana, Adrià (Date of defense: 2024-04-16)
The primary goal of this PhD is to deepen our understanding and improve the modeling capacity of zoonotic spillover, the multilevel process by which pathogens manage to overcome a series of natural ...
Elek, Anamaria (Date of defense: 2024-04-19)
Single-cell genomics methods have revolutionized the study of gene expression and regulation at the cell type level. Generating single-cell atlases for species at key phylogenetic positions of the animal ...
Martín de Dios, Laura (Date of defense: 2024-05-06)
La organización del genoma en células mamíferas sigue siendo en gran parte desconocida. Un nivel fundamental de organización se considera el bucle de cromatina, que consiste en una región de ADN atrapada ...
Menchetti, Mattia (Date of defense: 2024-06-07)
Biodiversity encompasses the great variety of organisms that exist on Earth, as well as their genetic variation and the ecosystems of which they are part. In this thesis, two diverse and ecologically ...
Costanzo, Maria (Date of defense: 2024-06-26)
Stem cell-based in vitro systems have recently been used to complement the study of developmental processes in the embryo. Somitogenesis, which segments a vertebrate body axis to establish its characteristic ...