Pedragosa Marín, Mireia (Date of defense: 2018-03-21)
The processes and mechanisms of virus infection fate decisions that are the result of a dynamic virus - immune system interaction with either an efficient effector response and virus elimination or an ...
Riera Domínguez, María Graciela (Date of defense: 2018-12-10)
The host immune response against infection requires the coordinated action of many diverse cell subsets that dynamically adapt to a pathogen threat. Due to the complexity of such a response, most ...
Peligero Cruz, Cristina (Date of defense: 2015-11-17)
Bloquejar la via PD-1/PD-L1 ha sorgit com una estratègia prometedora per a restaurar la resposta immune efectora en individus infectats amb el virus de la immunodeficiència humana (VIH). Malgrat l’extensa ...
Casella, Valentina (Date of defense: 2021-05-19)
The main aim of this project was to uncover the spatiotemporal events influencing type I interferon (IFN-I) dynamics during the early phase of acute and chronic viral infections. Time-resolved ...
Smutná, Katarína (Date of defense: 2019-02-18)
The process of HIV latency establishment and maintenance is not clearly understood. Homeostatic proliferation (HSP) is a major mechanism by which long-lived naive and memory CD4 T cells are maintained ...
Fleta Soriano, Eric (Date of defense: 2015-12-18)
Hundreds of host factors related to viral infections like HIV, hepatitis C virus, dengue virus or West Nile virus have been identified. As many of these host factors are shared by different viruses, ...
Domenjó Vila, Eva (Date of defense: 2022-06-01)
The contribution of cross-presenting XCR1+ dendritic cells (DC) in maintaining T cell function during exhaustion and immuno-therapeutic interventions of chronic infections remains poorly characterized. ...