Rodríguez Falcón, Manuel (Date of defense: 2010-10-07)
Normally present in water, soil and waste water, Acinetobacter baumannii has become an important nosocomial pathogen, as causal agent of pneumonias, septicemias and urinary tract infections, among ...
An, Weiteng (Date of defense: 2021-04-14)
Peptide-based vaccines have raised as an attractive alternative strategy to overcome many of the limitations of conventional vaccines. Some drawbacks for an optimal immune response in vivo are, a poor ...
Gallo, María (Date of defense: 2021-07-22)
This thesis focuses on one of the biggest challenges facing drug discovery field: the efficient targeted delivery of therapeutic compounds, and how cell-penetrating peptides (CPPs) acting as drug delivery ...
Ripoll Pastor, Greta (Date of defense: 2021-05-10)
Serologic tests detecting anti- T. gondii IgM are the gold standard for the diagnosis of acute toxoplasmosis. Nevertheless, most commercial kits are based on lysate antigens obtained from tachyzoites ...
Jiménez-Castells, Carmen (Date of defense: 2010-12-20)
Carbohydrate-binding proteins of non-immunological origin -lectins- have been recognized over the last decades as decisive players in numerous biological processes, ranging from cellcell communication, ...
Pérez-Peinado, Clara (Date of defense: 2020-01-20)
This work describes the discovery and optimization of efficient, selective, cost-effective and proteolytic-resistant antimicrobial and antitumoral peptides. To this end, we first identified novel ...
Forner, Mar (Date of defense: 2021-02-24)
Vaccination constitutes one of the most efficient and cost-effective methods of promoting global health. Nevertheless, few vaccines are fully effective, for manifold reasons ranging from intrinsic ...