Pazo Pelegrí, Esther (Date of defense: 2021-07-15)
At the end of G1 phase, cells have to decide between continue proliferation or remain in a quiescent state (G0). This decision point, known as “Start” in yeast and “Restriction Point” in metazoans, marks ...
Romão, Daniela (Date of defense: 2021-09-10)
Alterations in developmental transitions are common among animals to compensate for growth disturbances. These variations are usually a consequence of altered steroidal hormone production resulting in ...
Selfa Aspiroz, Idoia Lucía (Date of defense: 2022-02-01)
During the last years, the development of procedures to direct the differentiation of human pluripotent stem cells (hPSCs) towards different renal cell types has resulted in the establishment of approaches ...
Mòdol Cano, Aitor (Date of defense: 2021-04-29)
El cilio primario es una estructura formada por microtúbulos que sobresale de la superficie celular durante G0 teniendo una función de orgánulo sensor. La importancia del cilio es patente por las ...
Mestres Gonzalvo, Enric (Date of defense: 2022-02-18)
The embryo culture system is composed by all those elements with the potential to impact embryo development. Its optimization is required to stabilize in vitro embryo culture and produce reliable and ...
Sinigaglia, Barbara (Date of defense: 2022-11-25)
Several rainforest hunter-gatherer groups in south-east Asia are characterized by specific morphological features including a particularly dark skin color (D), an extremely short stature (S), the ...
Zamora Pérez, Paula (Date of defense: 2021-04-06)
Gold nanoparticle-modified polyelectrolyte nanocapsules present unique properties that allow them to generate luminescence and heat through exposure to light. Moreover, gold is a material extensively ...
Vogel González, Marina (Date of defense: 2021-09-03)
Zinc is an essential trace element with structural, catalytic and signaling roles in our body. At cellular level, zinc homeostasis participates in fundamental functions such as cell proliferation, ...
Martínez Ara, Guillermo (Date of defense: 2022-09-19)
During embryonic development, cellular forces synchronize in space and time to generate functional tissue shapes. Apical constriction is a force-generating process necessary to provoke the folding of ...
Häkkinen, Hanna-Maria (Date of defense: 2022-07-01)
Cellular errors can spontaneously occur during vertebrate embryo development and can lead to apoptosis. Recent work in our lab revealed a novel function of the embryonic epithelium as an efficient ...