Torrens Fontanals, Mariona (Date of defense: 2022-02-11)
Molecular dynamics (MD) simulations are a well-established technique to characterize the structural motions of biological systems at atomic resolution. However, accessing, viewing, and sharing MD ...
Garriga Nogales, Edgar (Date of defense: 2022-02-15)
In these days of significant changes and the rapid evolution of technology, the amount of datascience has to deal with the growth incredibly fast, and the size of data could be prohibitive.Multiple ...
Moreno Lama, Lucía (Date of defense: 2020-01-16)
Los inhibidores de PARP han surgido como nuevas terapias basadas en el papel essencial de las Poly (ADP-ribosa) polimerasas PARP-1 y PARP-2 en la respuesta a daño en el DNA, explotando el efecto de las ...
Escrich Montañana, Ainoa (Date of defense: 2022-12-01)
The emergency to obtain effective substances against cancer, and the awareness to protect natural resources make plant biofactories a promising alternative for obtaining plant-derived compounds. In this ...
Tassinari, Andrea (Date of defense: 2020-05-19)
Mendieta Esteban, Julen (Date of defense: 2020-12-10)
Genome spatial organisation and transcriptional activity are tightly coordinated to ensure the correct function of the cell. Thus, proper understanding of the chromatin organisation is needed to deepen ...
Mestre-Farrera, Aida (Date of defense: 2020-02-27)
Tumors are complex tissues composed by multiple cell types, such as cancer associated fibroblasts (CAFs), that facilitate the invasive behavior of tumor cells. When we examined their nutrient requirements, ...
Hovhannisyan, Hrant (Date of defense: 2020-12-15)
Candida pathogenic yeasts represent a global healthcare problem. They comprise phylogenetically diverse species, including newly emerged pathogens. How human-Candida interactions vary across species, ...
Aguirre Plans, Joaquim (Date of defense: 2021-07-14)
El funcionament intern de les cèl·lules pot entendre’s com un conjunt d’interaccions entre biomolècules, formant una xarxa que coneixem amb el nom d’interactoma. Els fàrmacs i malalties poden considerar-se ...
Balbastre Català, Borja (Date of defense: 2022-10-27)
Dual-specificity tyrosine-regulated kinases (DYRKs) are a conserved family of protein kinases present in all eukaryotes. In mammals, the association of DYRKs with a wide variety of putative substrates ...