Mostrando ítems 1-10 de 15
Aparicio i Prat, Estel (Fecha de defensa: 2014-02-07)
Non-coding RNA functions are emerging in the recent years. In this thesis we describe a Natural Antisense Transcript (NAT) that controls the expression of LEF1 transcriptional factor. This LEF1 NAT ...
Mestre-Farrera, Aida (Fecha de defensa: 2020-02-27)
Tumors are complex tissues composed by multiple cell types, such as cancer associated fibroblasts (CAFs), that facilitate the invasive behavior of tumor cells. When we examined their nutrient requirements, ...
Olivera-Salguero, Rubén (Fecha de defensa: 2019-07-19)
Snail1 is the master regulator of the Epithelial-to-Mesenchymal Transition (EMT) and is also crucial for fibroblast activation upon TGFβ signaling. In cancer, Snail1 expression in primary tumors correlates ...
Batlle Gómez, Raquel (Fecha de defensa: 2011-12-19)
The Snail1 transcriptional repressor is a key factor responsible in triggering epithelial to mesenchymal transition. Although Snail1 is widely expressed in early development, it is limited in adult ...
Viñas Castells, Rosa (Fecha de defensa: 2013-05-24)
Epithelial to mesenchymal transition (EMT) is a process by which epithelial cells acquire a mesenchymal phenotype. It is characterized by the down-regulation of the adherens junction protein E-cadherin, ...
Millanes Romero, Alba (Fecha de defensa: 2014-01-21)
Although heterochromatin is enriched with repressive traits, it is actively transcribed, giving rise to large amounts of non-coding RNAs. These transcripts are responsible for the formation and ...
Porta de la Riva, Montserrat (Fecha de defensa: 2009-09-22)
La transició epiteli-mesènquima (TEM) és un procés en què cèl lules epitelials, immòbils i amb polaritat apico-basal transiten cap un fenotip mesenquimal o fibroblàstic. L'expressió del factor de ...
Cabrerizo Granados, David (Fecha de defensa: 2020-11-30)
Snail1 is a transcriptional factor with a great relevance in tumor development as it is required for epithelial to mesenchymal transition and activation of cancer-associated fibroblasts (CAF). In this ...
Lambies Barjau, Guillem (Fecha de defensa: 2019-01-10)
Cancer cells undergo epithelial-to-mesenchymal transition (EMT) to dissociate from the primary tumor and to survive to chemotherapy. EMT is controlled by Snail1, a transcriptional factor also required ...
Escrivà Izquierdo, María (Fecha de defensa: 2008-06-20)
The product of the snail1 gene (SNAIL1) is a transcriptional repressor required for triggering the epithelial-to-mesenchymal transition (EMT). SNAIL1 transcription is induced when epithelial cells are ...