Mostrando ítems 1-7 de 7
Lloret Llinares, Marta (Fecha de defensa: 2011-05-17)
La metilació de les lisines de les histones està implicada en les funcions associades a la cromatina, com l’expressió gènica o la formació d’heterocromatina. És una modificació covalent afegida per ...
Mendieta Esteban, Julen (Fecha de defensa: 2020-12-10)
Genome spatial organisation and transcriptional activity are tightly coordinated to ensure the correct function of the cell. Thus, proper understanding of the chromatin organisation is needed to deepen ...
Fraile Beneitez, Rodrigo (Fecha de defensa: 2021-07-23)
Eukaryotic DNA is condensed inside the nucleus, compacted into chromatin. The structure of chromatin is dynamic, and its accessibility to cellular machinery can be altered depending on the level of ...
Iannone, Camilla (Fecha de defensa: 2014-05-23)
Intron removal is a necessary step for expression of most genes in higher eukaryotes, and alternative splice selection is a highly regulated mechanism that endows a single gene with the possibility to ...
Teichmann, Sophie (Fecha de defensa: 2013-02-04)
La monoubiquitinación de la histona H2A cumple un rol esencial en la represión génica. Diversas enzimas desubiquitinantes (DUBs) han sido identificadas, que remueven específicamente la ubiquitina de ...
Viéitez Manrique, Cristina (Fecha de defensa: 2014-12-18)
In response to fluctuations in the environment, all living organisms have the ability to sense, respond and adapt to the new conditions. In budding yeast (Saccharomyces cerevisiae) there is a massive ...
Mejetta, Stefania (Fecha de defensa: 2013-09-12)
Jarid2 is required for the genomic recruitment of the polycomb repressive complex-2 (PRC2) in embryonic stem cells. However, its specific role during late development and adult tissues remains ...