Ara mostrant els elements 1-7 de 7
Di Stefano, Bruno (Data de defensa: 2014-06-05)
One of the major goals of current stem cell research is understanding the mechanism of somatic cell reprogramming by Oct4, Sox2, Klf4 and Myc (OSKM) into induced pluripotent stem cells (iPSCs). However, ...
Sesé Ballesteros, Borja (Data de defensa: 2013-07-05)
Embryonic stem (ES) cells are able to differentiate into any cell type, a property called pluripotency, and have unlimited potential for self-renewal. Although the molecular mechanisms responsible for ...
Morral Martínez, Clara (Data de defensa: 2017-07-17)
El càncer de colon es caracteritza per presentar una composició cel·lular heterogènia en la qual només un subgrup de cèl·lules retenen la capacitat de contribuir en el manteniment i creixement del tumor. ...
Pecoraro, Matteo (Data de defensa: 2014-10-02)
La senescencia celular es una detención irreversible del ciclo celular que tiene lugar en respuesta a diversos estímulos de estrés, actuando como un mecanismo supresor de tumores para impedir la ...
Ritschka, Birgit (Data de defensa: 2017-09-15)
Cellular senescence has mainly been associated with tumor suppression and aging, mediated through cell intrinsic cell-cycle inhibition and arrest. However, through secretion of specific proteins, termed ...
Toufighi, Kiana (Data de defensa: 2014-10-31)
Over the last several decades, the emerging ‘integrated’ view of the cell has triumphed over the ‘one gene/one protein/one function’ paradigm. This is illustrated by the biologically opposite effects ...
Simonte, Giacoma (Data de defensa: 2016-12-14)
My PhD project was focused on understanding if endogenous bone-marrow cells (BMCs) could participate in the repair of mouse retina following N-Methyl-D-aspartate (NMDA) damage. We wanted to explore the ...