Colomer-Lahiguera, Sara (Date of defense: 2015-11-19)
T-cell acute lymphoblastic leukemia (T-ALL) accounts for 10 15% of pediatric ALL. The oncogenic transformation of T-cell precursors is driven by a broad spectrum of genetic abnormalities. We have confirmed ...
Vicario Orri, Elena (Date of defense: 2017-10-03)
The mechanisms by which amyloid beta (Aβ) causes synaptic dysfunction in Alzheimer’s disease (AD) remain elusive. Aβ is derived by sequential cleavage of the amyloid precursor protein (APP) and released ...
Guix Ràfols, Francesc Xavier (Date of defense: 2009-01-22)
Aquesta tesi demostra que el peroxinitrit produït com a conseqüència del pèptid beta-amiloide (A) contribueix l'augment de la relació A42/A40 que ocorre a la malaltia d'Alzheimer. ...
Núñez Ollé, Marc (Date of defense: 2014-07-04)
Cyclin O, a novel identified CDK1 and CDK2-binding cyclin, has been demonstrated to be required for γ-radiation induced apoptosis in a lymphoid cell line. Ɣ-radiation induces the formation of DSBs in ...
Martínez-Jiménez, Francisco (Date of defense: 2016-12-16)
Most of the cellular functions are driven by small-molecules that selectively bind to their protein targets. Is such their importance, that the pharmacological intervention of proteins by small molecule ...
Maliar, Serguei (Date of defense: 1999-09-08)
La tesis se centra en las aplicaciones macroeconómicas del consumidor representativo. El primer capítulo analiza la posibilidad de agregación en economías con varios bienes y varios periodos. Desarrollo ...
Amatriain, Xavier (Date of defense: 2005-01-27)
Classical models for information transmission such as Shannon and Weaver's still tend to be looked at as the only possible scenarios where signal processing applications can be formally modeled. Meanwhile, ...
Grachten, Maarten (Date of defense: 2006-11-05)
La recerca presentada en aquesta dissertació glossa sobre transformacions de tempo de gravacions monofòniques de saxo jazz preservant l'expressivitat musical. Es una contribució al processament d'audio ...
Zacharaki, Konstantina Eirini (Date of defense: 2022-02-24)
Infants start their lives with a universal ability to perceive speech and during the first months of life they attune to the language(s) they are exposed to in their environment, i.e. perceptual narrowing. ...
Pereira, Carolina Ruivo (Date of defense: 2016-10-24)
El cáncer de pulmón es la forma más mortal de cáncer en el mundo. Recientemente, el estudio del perfil genómico a larga escala de tumores humanos ha impulsado el desarrollo de drogas que tienen como ...