Universitat Pompeu Fabra: Enviaments recents
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La raíz imaginada: Javier Cercas, biografía de una obra literaria
El siguiente documento estudia la obra de Javier Cercas desde su primera publicación, El móvil (1987) hasta el reciente título del nuevo ciclo de novelas iniciado con Terra Alta (2019). La tesis consta de cinco partes. ...
Plant processing activities and the use of domestic space at Neolithic Çatalhöyük, Turkey: A microbotanical perspective
Çatalhöyük is a 9,000-year-old settlement located in the Konya Plain, Turkey. Thanks to the remarkable preservation of its material culture, Çatalhöyük expanded our understanding of the neolithic lifeways in what was one ...
Phytoliths as proxies for plant water availability: An experimental approach on selected C4 species and its archaeological application in drylands
Este trabajo investigó la relación entre los fitolitos de mijo de dedo, mijo perla y sorgo, y las condiciones hídricas en las que crecen estas especies. El debate arqueológico sobre el uso de los mijos sigue abierto y ...
Novel methods for multiple sequence alignment and evolutionary modeling
El continuo aumento de los proyectos de producción de datos genómicos a gran escala, como el "Earth BioGenome Project" (Lewin et al., 2018), pone los métodos de análisis de datos bajo una presión sin precedentes. Es necesario ...
Chromatin-linked and NF-kB independent IkBa function in embryonic stem cell pluripotency exit and differentation
Pluripotent stem cells (PSCs) have the ability to self-renew and give rise to almost every somatic cell type. Because of their enormous potential as a tool for regenerative medicine, understanding molecular mechanisms that ...
Outdoor exposure to residential noise, neurodevelopment, and sleep in children and preadoslescents
Environmental noise pollution has become a major public health concern due to its increase during the last decades as a result of urbanization processes. Environmental noise can be produced by different sources but the ...
Population genetics of Copy Number Variants: the case of the Romani population
Much information has been gathered for the Romani population so far, spanning historical, linguistics and genetics research. While whole genome analyses for this population started only recently, most studies using genetic ...
Impact of recent protein structure prediction methods on homology, evolutionary and functional inference
Recent advances in deep learning techniques have revolutionised protein structure modelling. Since AlphaFold2’s release, a set of tools have now become available to predict native-like structures at near-experimental ...
Zero-knowledge proofs for self-sovereign identities in decentralized services
Telecommunication systems such as mobile communications are evolving over time, and thanks to that, many digital services have arisen in the last decade. Usually, these services ask their users to provide sensitive information ...
Thai TV series brought to Spanish-speaking audiences: a study of fansubbing practices
This thesis investigates the complexities of the fansubbing of Thai TV series into Spanish as a representative case of two underexplored areas in Translation Studies: non-professional translation and pivot translation. ...
Exploring graphic pathographies construction: a multimodal analysis
In the last couple of years, medical information has been presented across different digital and visual forms of communication. Mainly, comics are published on various social media platforms and websites to submit a ...
Machine translation in a professional translation workflow: post-editing or computer aided translation
Localization is a fascinating field which has changed dramatically in the last years and it is still changing and adapting itself as society is. The use of machine translation has developed this field astonishingly. Many ...
Developing a multimodal pedagogical approach for English literature teaching
In the field of teaching English literature to Spanish adolescents, a multimodal approach offers diverse modes of representation and brings potential for meaning making. However, teaching with digital technology or using ...
Charting the heterogeneity of healthy and malignant immune cells, one cell at a time
Specialization and plasticity are hallmarks of immune cells. Thus, charting their heterogeneity is crucial to understand their function and role in diseases. In this setting, single-cell RNA-sequencing (scRNA-seq) has ...
Decoding the immune evasive properties of cancer stem cells in breast cancer immunotherapy resistance
Cancer stem cells (CSCs) fuels tumours and are involved in therapy resistance, yet their contribution immunotherapy resistance and immunological properties are poorly understood. Herein, we show that within tumour phenotypic ...
Greener on the other side?: greenspace exposure and cardiovascular health
The last century has been marked by perhaps the greatest demographic transition in human history. The processes related thereto, such as rapid urbanization and population ageing, pose a major public health concern, and ...
Análisis de contenidos y resultados diagnósticos en la evaluación del trastorno depresivo mayor
Introducción: El Trastorno Depresivo Mayor (TDM) es una enfermedad común que limita severamente el funcionamiento psicosocial y disminuye la calidad de vida. Clínicamente, el diagnóstico pasa por la entrevista clínica ...
Essays on international trade and economic geography
This thesis explores how international trade shapes economic geography and analyses the effects of borders and other trade costs on the pattern of trade. In the first chapter, I study how the reduction in trade costs ...
Genetic associations on major depression: curation and functional analysis
Major depression (MD) is the leading cause of impairment worldwide. The lack of understanding of its biological underpinnings hampers the development of better diagnostic tools and treatments. Thanks to the advances in ...
The Role of the LRRC8A anion channel in adaptation to stress
Cell volume regulation is essential for cellular homeostasis and adaptation to environmental osmotic changes. Upon hyperosmotic stress, cells need to rapidly restore osmotic balances in order to preserve the function of ...
