Universitat Pompeu Fabra: Recent submissions
Now showing items 341-360 of 3325
International juridical double taxation and individuals' ability to pay in the light of EU law
According to the CJEU’s case law, the tax disadvantage suffered by taxpayers in a cross-border situation arising from international juridical double taxation does not constitute a forbidden obstacle to free movement because ...
A Genome-wide CRISPR screen to identify novel pathways involved in reprogramming and x-chromosome reactivation
During reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), the epigenome needs to be reset. A prime example of this is the reversal of the silent state of the inactive X chromosome in female cells, ...
Occupational heat exposure and cancer risk
Heat exposure is a growing concern for many workers around the world as climate change is causing global average temperatures to rise. Heat exposure has been linked to a number of key carcinogenic processes, but current ...
La financiación ilegal de los partidos políticos: un estudio sobre la intervención penal en la materia
La tesis elaborada centra su objeto de estudio en la financiación ilegal de los partidos políticos, en particular, en la intervención y respuesta penal en este ámbito. La principal meta que persigue el estudio es dilucidar ...
Two mental disorders as disease models of language: linguistic (dis)organisation in schizophrenia and Huntington's disease
Language is a core aspect of human cognition and richly interacts with aspects of nonverbal cognition, as evidence from normal development (Perszyk & Waxman, 2018), abnormal development (Schroeder et al., 2020), and aphasia ...
La difamación lingüística : delito, concepto y sistema
En esta investigación haremos un análisis sistemático-conceptual del delito de difamación lingüística desde una perspectiva suprapositiva. Para ello, usaremos nociones propias de la teoría del lenguaje vinculadas a esta ...
Smart legal contracts: el uso de tecnologías emergentes para la automatización de todo o parte del ciclo de vida del contrato
El uso de las tecnologías emergentes de registro distribuido y las tecnologías que se enmarcan bajo el término paraguas "inteligencia artificial" para la automatización (total o parcial) del ciclo de vida del contrato, ...
Cellular dynamics and molecular mechanisms underlying the 3D organization and connectivity of the statoacoustic ganglion
The statoacoustic ganglion (SAG) is a complex 3D structure composed by neurons in charge of transmitting the information from inner ear hair cells to the CNS. During development, SAG copes with otic tissue demands to ...
Phylogenomic insights into the evolution of subterranean Coleoptera
Under very specific pressures, evolution turns extremely convergent, to the extent that distantly-related organisms show highly similar morphological, physiological and behavioral adaptations. Life into the perpetual ...
Translational control by differential expression of tRNAs
Malgrat teixits diferents presenten diferències en l'ús de codons i en els repertoris d'anticodons dels ARNt, el coneixement sobre la co-adaptació entre codó-anticodó en eucariotes multicel·lulars és incomplet. D'una banda, ...
Understanding evolution through genomic analysis of extinct species
According to estimates, over the 3.5 billion years that have elapsed since the appearance of life, the Earth has been inhabited by some 4 billion different species, of which 99.99% have already become extinct. Extinction ...
La forma-ritual del cine de Chantal Akerman: hacia un espectador encarnado
Esta investigación nace de la necesidad de repensar los aportes estéticos del cine de Chantal Akerman, a los cuales me aproximo tratando de dar una posible respuesta a la pregunta, ¿en qué forma el cine de Akerman llega ...
Accesibilidad y usos positivos aplicados de la realidad extendida (virtual, aumentada y mixta) para personas con movilidad reducida: hacia un Metaverso inclusivo
Las tecnologías de la Realidad Extendida (XR) presentan retos de accesibilidad para las personas con movilidad reducida (PCMR), aunque también oportunidades que pueden beneficiar su bienestar. Para abordar ambos aspectos, ...
Filmar las palabras
El presente trabajo de investigación se propone analizar los modos en que el cine ha llevado a cabo el acto de filmar los textos literarios. En oposición a la tendencia convencional en los estudios filmoliterarios que ...
Genetic adaptation in underrepresented populations: the cases of Peruvian and North African populations
As a result of local selective pressures, genetic adaptation leaves distinct recognisable marks in the genomes of human populations. Several cases of positive natural selection have been described in humans, but only in a ...
La vigilancia epidemiológica desde una aproximación sindémica: la vigilancia de las infecciones de transmisión sexual y de la tuberculosis centrada en poblaciones a riesgo de infección
El propósito principal de la tesis es contribuir en lo posible a potenciar la vigilancia de las pandemias de las infecciones de transmisión sexual (ITS) y la tuberculosis (TB) en las poblaciones a riesgo de infección a ...
Interplay between cancer cells, fibroblasts, immune cells, and resistance to PD-1/PD-L1 inhibition in breast cancer
Although the dual anti-HER2 blockade with trastuzumab and pertuzumab monoclonal antibodies has improved the outcome of patients with HER2+ breast cancer, a significant number of patients relapse. Additional strategies for ...
Temporal and spatial patterns differences of basal and cognitive brain states
Dynamic brain states, temporal functional unions of diverse brain areas, are the driving force in our everyday cognition. They help us to flexibly integrate and segregate the assorted information that the environment is ...
Targeting BRAF mutant pre-mRNA alternative splicing in melanoma
Alternative splicing of BRAF mRNA can provide a resistance mechanism to BRAF and MEK inhibitors that has been described mostly in BRAF-mutant melanoma. The mechanisms underlying the production of a variety of BRAF mRNA ...
Information structure and language dominance in subject pronoun resolution in Catalan-Spanish bilingualism
Pronominal anaphora resolution, and particularly the interpretation of third-person null and overt subject pronouns, is a complex linguistic phenomenon of the syntax-pragmatics interface. On the one hand, it has been ...
