Universitat Pompeu Fabra: Recent submissions
Now showing items 201-220 of 3325
Computational studies of DNA damage and repair of alkylating agents and UV light
Living cells are exposed to naturally occurring DNA-damaging agents that promote the loss of genome integrity, threatening the proper functioning of the cell. To counteract the toxic accumulation of DNA damage, organisms ...
Predicting effects of stroke lesions and recovery through whole-brain modeling and brain dynamics
Stroke is the second leading cause of death worldwide and a major contributor to disability. However, our understanding of the consequences of stroke lesions remains limited, relying mainly on behavioral reports and ...
Molecular mechanisms during the differentiation, maturation and function of marine fish spermatozoa
The molecular mechanisms regulating sperm differentiation (spermiogenesis) and maturation in fishes are largely unknown. In these oviparous species, the initiation of sperm motility is triggered by the osmolality of the ...
Reconstructing Empire: Spain, Cuba, and the United States, 1861-1886
This thesis explores the interconnections between the U.S. and the Spanish Empire in the late 19th century, adopting an approach that departs from the traditional historical narratives that have considered these histories ...
Crops and Environment in the Lower Indus Plain During the Bronze Age : A Multi-proxy Approach to the Agricultural Strategies of the Indus Valley Civilization
The Indus Valley Civilisation (IVC) is the earliest known urban culture of South Asia (2600-1900 BCE). While archaeological research has been conducted in the region for over a century, systematic archaeobotanical analyses ...
Essays on Macroeconomics and Textual Analysis
Aquesta tesi conté tres assaigs sobre macroeconomia i anàlisi textual. En el primer capítol, estudio l’impacte de la polarització política sobre les polítiques mediambientals utilitzant propostes de llei de les ...
El Llull d'En Foix: L'Ars lul·liana en el desenvolupament de la investigació en poesia
El poeta J. V. Foix desplega en l’obra literària i assagística una intensa i ininterrompuda recepció, interpretació i apropiació de la matèria lul·liana. Alguns aspectes de l’Ars de Ramon Llull, dels quals destaquem ...
Interpretable deep-learning models for sound event detection and classification
Deep-learning models have revolutionized state-of-the-art technologies in many research areas, but their black-box structure makes it difficult to understand their inner workings and the rationale behind their predictions. ...
Multilingual retrieval of crisis-relevant information from social media
Social media is a valuable platform for sharing real-time perspectives and insights, particularly during dynamic events. Extracting relevant information from social media during emergencies can be challenging, especially ...
Writer-reader relationship and technicality of vocabulary in multilingual health information websites in English, Spanish, and Catalan
The purpose of the thesis is to investigate multilingual health information websites in English, Spanish, and Catalan for comprehensibility and cultural adaptation in terms of language. This study questions whether there ...
Proximal junctional failure stratification in adult spine surgery using 3D patient-specific finite element models
Adult Spine Deformity (ASD) leads to abnormal spine curvature causing imbalance, pain, and fall risk. Spinal surgery is common but carries the risk of Mechanical Complications (MC), notably Proximal Junctional Failure ...
On the flexibility of the perception and cognition of broken harmonic expectations
La música està present en totes les cultures. Tot i tenir les mateixes habilitats auditives, la manera en la què experimentem la música depèn del context cultural, la música que escoltem en el dia a dia o si hem rebut ...
Diversity and evolution of South Pacific Eumolpinae (Coleoptera: Chrysomelidae) and the role of New Caledonia in their diversification
The South Pacific is an intriguing region for studying evolutionary biology, presenting an exceptional diversity and complex geological and environmental characteristics. New Caledonia, in particular, hosts a rich and ...
Lifestyle interventions and cognitive change: determinants and underlying mechanisms
Les intervencions que milloren l’estil de vida (dieta, exercici físic i entrenament cognitiu) poden frenar el declivi cognitiu en persones a risc de demència. En el context d’intervencions en l’estil de vida, aquesta ...
Computational engineering of biomolecules
Aquesta tesi presenta diversos avenços que inclouen: (i) noves funcionalitats afegides a la “suite” d'eines de disseny de proteïnes FoldX per permetre als usuaris treballar amb qualsevol tipus de molècula; (ii) estudis ...
Deciphering the nuclear function of folate enzyme MTHFD2 in cancer: a novel role for nuclear MTHFD2 in mitosis
Subcellular compartmentalisation of metabolic enzymes may elicit specific cellular functions by establishing a unique metabolic environment. Indeed, the nuclear translocation of certain metabolic enzymes impacts epigenetics ...
Dynamics of cellular decision making in embryogenesis
This thesis is about development and its study from a theoretical point of view, with special interest in how to describe development as a dynamical systems' problem. The thesis digs into four directions embedded in this ...
Information fusion and learning from diverse clinical cohorts and heterogeneus data
This PhD thesis explores how data science can be leveraged to learn from diverse cohorts and fuse information from heterogeneous data, aiming to advance understanding and improve prediction in healthcare settings. It covers ...
Processing of sentential meaning: behavioural and electroencephalographic evidence in neurotypical and Williams syndrome adult populations
Meaning in any naturalistic utterance has a dual aspect: one is lexical-semantic memory, which enters into utterances in the form of words that we remember and retrieve; the other is the specific kind of meaning carried ...
Multimodal phonetic training: the benefits of hand gestures on learning L2 sounds
In the realm of second language acquisition of pronunciation, perception-based phonetic training has been shown to be effective in improving L2 perception and production. By incorporating the visual modality of the speaker’s ...
