Universitat Pompeu Fabra: Recent submissions
Now showing items 221-240 of 3276
Essays in industrial organisation
This thesis contains three chapters, each developing a theory and providing evidence on a unique and novel determinant of firms’ outcomes in the emerging and developed economies of 21st century. The first chapter examines ...
Evolution of tissue-specific transcriptomes across bilaterian animals
Regulated Gene Expression (rGE) and Alternative Splicing (rAS) are two of the main mechanisms contributing to tissue-phenotypic diversity within and between species. In this thesis, we aim at characterizing rGE and rAS ...
Assessment of CRISPR-based genome editing tools for enhancing precision: a computational platform and novel factors for homology-directed repair
Precision and accuracy are paramount for the use of genome editing in clinic, environmental, and industrial applications. These fields require reliable and traceable results to ensure the safety and viability of the resulting ...
Genomic signatures of conditional selection in different copy number states in human cancers
Determinar qué genes están bajo selección durante la evolución del cáncer puede explicar cómo se forman y progresan los tumores, y sugerir nuevos objetivos terapéuticos. Sin embargo, la detección de selección utilizando ...
Essays on inequalities in economics of labor and education
This thesis studies inequalities in the areas of education and labor markets, as well as public policies designed to reduce these inequalities. The first chapter studies whether part-time work options in paid parental ...
Mirrors with unflattering reflections: moral rebels as fuel for social inertia or social change?
Individuals who deviate from majority practices based on moral objections can be crucial catalyzers of social change. However, according to prior work, these “moral rebels” are commonly met with defensiveness. Therefore, ...
Using virtual reality to train public speaking skills in a secondary school setting
Training adolescent students to speak in public is crucial for the development of their oral competence but also beneficial for their social abilities, as it empowers them to engage in learning opportunities among their ...
¡Tiranos, temblad! Ejército y milicias de Montevideo en la crisis del Imperio (1750-1811)
Este trabajo propone un análisis sobre la guarnición militar de Montevideo desde su creación hasta el estallido de la Revolución Oriental en 1811. Su objetivo es analizar la actuación del ejército y las milicias que allí ...
Retrato de un perdedor: el último virrey de Nueva Granada Juan de Sámano
A través de un seguimiento biográfico y cronológico, desde su nacimiento en 1753 en la Provincia de Selaya, Cantabria hasta la Ciudad de Panamá el 1 de agosto de 1821 fecha de su muerte, se construirá el retrato del último ...
Los personajes femeninos creados por autoras latinoamericanas en la dècada de los 80: Una aproximación a la obra de Isabel Allende, Ángeles Mastretta y Gioconda Belli
Esta investigación explora los puntos comunes entre la realidad histórico-biográfica y la recreación literaria en tres novelas finiseculares publicadas por autoras hispanoamericanas: De amor y de sombra (1984), de Isabel ...
Descolonizando el Gadir fenicio: Convivencia y multiculturalidad en la Bahía de Cádiz (siglos IX-VI a.n.e.)
Colonia, colonialismo o colonización son términos y conceptos muy recurrentes en las reconstrucciones históricoarqueológicas del pasado. Los movimientos migratorios que se desarrollaron en el Mediterráneo y Atlántico ...
Complexity changes in neuroimaging signals point to mechanisms of neuropsychiatric disease
The past decade has seen several attempts to employ the entropy of neuroimaging signals as a potential biomarker for cognitive decline or traumatic brain injury (C. Y. Liu et al. 2013; Adhikari et al. 2017; Li et al. 2018). ...
The calculation of damages in EU intellectual property law: an assessment of the harmonisation approach used in article 13(1) of Directive 2004/48/EC on the enforcement of IPRs
The claim for compensation is a key tool in any legal system. Due to their ubiquitous nature, the calculation of damages for the infringement of intellectual property rights exhibits significant peculiarities. In its ...
US Latina/o/x migrations, translations and routes of reception: an integrated critique
The object of study of this thesis is a special case of translation: the Anglophone literature of writers of Caribbean or Latin American origin in the United States translated into Spanish. This case is special because of ...
The effect of foreign language on emotion regulation
Hay personas que se pueden enfrentar, por unas razones u otras, a un tratamiento terapéutico en un idioma que no es su idioma nativo. Hasta la fecha, no hay apenas información de qué efecto tendría usar una lengua no nativa ...
Towards a statistical physics of major evolutionary transitions: information, thermodynamics and ecology at the mathematical foundations of evolution
This thesis aims at establishing the basis for a statistical physics theory of major evolutionary transitions. Its structure is based on three major pillars: nonequilibrium thermodynamics and information theory, stochastic ...
Essays in safe assets: trends, drivers and implications for financial stability
This dissertation consists of three chapters centred on safe assets, shedding light on different aspects of the growing literature on the subject. Chapter 1 introduces the set of assets that falls under the safe category, ...
Essays in time series econometrics
This doctoral thesis develops new methods for time series analysis and applies these to prominent empirical problems in macroeconomics. It contains three chapters. Chapter one proposes a new non-parametric generalized method ...
Unveiling the role of Her9/Notch pathway in the maintenance of stemness in the hindbrain boundaries
The generation of cell diversity in the embryonic brain relies on the balance between cell proliferation and differentiation. The hindbrain boundary cells specify at the interface between adjacent compartments. Boundary ...
Super-resolution imaging uncovers key temporal changes in chromatin structure and pluripotent gene reactivation in single reprogramming cells
Elucidating the mechanism of somatic cell reprogramming has been hampered by the limitations of iPSC systems to uncover the correctly reprogramming cells. Here, by using the highly efficient heterokaryon system we dissected ...
