Now showing items 21-40 of 57

    Desenvolupament i beneficis per a la salut d'una aplicació mòbil basada en els problemes pediàtrics no urgents 

    Perruca Martínez, Cristina (Date of defense: 2022-03-04)

    The lack of knowledge and skills in the care of infants in their first years of life often results in frequent paediatric consultations for banal problems and doubts, which are often a result of a low level of health ...

    Desenvolupament i implementació clínica d’un nou dispositiu en tècniques d’inspiració forçada mantinguda en tractaments de càncer de mama esquerra amb radioteràpia externa per reduir la dosi al cor 

    Romera Martínez, Ingrid (Date of defense: 2024-12-05)

    ENG- The radiotherapy treatment for left breast cancer is widely described. One of the long-term undesirable effects of radiotherapy is heart disease, which often manifests as ischemia or myocardial infarction, especially ...

    Design and fabrication of three-dimensional scaffolds for breast cancer stem cell expansion and molecular characterization 

    Rabionet Diaz, Marc (Date of defense: 2021-11-08)

    Triple negative breast cancer (TNBC) accounts for 15-20% of the breast cancers and displays an aggressive profile, poor prognosis, high relapse risk and does not have a targeted therapy. In the last years, breast cancer ...

    Dietary patterns in the etiology of lymphoid neoplasms 

    Solans Margalef, Marta (Date of defense: 2019-10-14)

    Diet is a key modifiable risk factor for several neoplasms, but evidence for lymphoid malignancies is still inconsistent. Previous epidemiological studies were mostly focused on single dietary components (i.e. nutrients ...

    DNA methylome in HER2-positive resistant breast cancer 

    Palomeras, Sònia (Date of defense: 2019-02-27)

    The major clinical problem for HER2+ breast cancer target therapies is the acquisition of resistance. The DNA methylation status of the promoter gene region has been described as a common epigenetic alteration for ...

    Estudi de l'acció de diferents bloquejadors de la via ErbB en la teràpia antitumoral 

    Ferrer Soler, Laura (Date of defense: 2007-03-30)

    L'inhibidor de carboxipeptidasa de patata (PCI) és un antagonista de l'EGF. Un dels problemes del PCI, però, és la baixa afinitat per l'EGFR en comparació amb el lligand natural. En aquest treball s'han dissenyat nous ...

    Estudi epidemiològic poblacional de la incidència, tendència i supervivència de les neoplàsies limfoides a la província de Girona durant un període de 20 anys (1996-2015) 

    Auñón Sanz, M. del Carmen (Date of defense: 2020-11-20)

    The incidence, time trends and survival of lymphoid neoplasm’s in the Girona province are analyzed from 1996 to 2015. The survival of diffuse large B-cell lymphoma (LBDCG) before and after 2004 and estimate incidence rate ...

    Estudio del impacto de UGT2B17 y PD-1 en el trasplante alogénico de progenitores hematopoyéticos a partir de donante emparentado HLA idéntico 

    Santos Carvajal, Nazly (Date of defense: 2022-11-25)

    Study of the impact of UGT2B17 and PD-1 on allogeneic transplantation of hematopoietic progenitors (allo-TPH) from HLA-identical related donor. everal genetic factors can favor the development of graft-versus-host disease ...

    Factors pronòstics en la dehiscència anastomòtica de la cirurgia del càncer de còlon. Models de predicció actuals i validació externa independent 

    Pigem Rodeja, Anna (Date of defense: 2023-03-03)

    INTRODUCTION: Anastomotic leak (AL) is the most dreadful and life-threatening complication in colon cancer (CC) surgery. It is associated to an increase of morbimortality, longer hospital stay, increased healthcare costs ...

    Fatty acid synthase expression and inhibition in cancer 

    Blancafort Jorquera, Adriana (Date of defense: 2016-01-29)

    In this thesis,the association of FASN (fatty acid synthase) expression with clinicopathological and anthropometric characteristics in breast cancer patients is studied to find out FASN role as a prognostic in early stage ...

    Fatty acid synthase expression and inhibition in triple-negative breast cancer 

    Giró Perafita, Ariadna (Date of defense: 2017-01-17)

    Triple-negative breast cancer (TNBC) represents 20% of breast cancer and patients receive only general chemotherapy. The epidermal growth factor receptor (EGFR) is commonly expressed in TNBC and it is associated with poor ...

    Fenotipado de las mutaciones NRAS en cáncer colorrectal: caracterización clínico-molecular y búsqueda de nuevas terapias 

    Queralt, Bernardo (Date of defense: 2024-09-30)

    ENG- Metastatic colorectal cancer (mCRC) remains a major medical challenge, particularly in the search for effective treatments such as epidermal growth factor receptor (EGFR)-targeted therapies. While mutations in the ...

    Glandular tissue pattern analysis through multimodal MRI-mammography registration 

    García Marcos, Eloy (Date of defense: 2018-04-05)

    Breast cancer is the most common cancer among women worldwide. Several studies have shown that the combination of the different medical image modalities, such as the x-ray mammography and the magnetic resonance imaging ...

    Glycan alterations of serum proteins as tumour markers. Prostate-specific antigen in prostate cancer and acute-phase proteins in pancreatic cancer 

    Sarrats Carbó, Ariadna (Date of defense: 2011-02-10)

    Els pacients amb càncer presenten una taxa de supervivència superior si es diagnostiquen a estadis inicials, per la qual cosa és indispensable disposar de marcadors tumorals adequats. Glicoformes de proteïnes específiques ...

    Històries de malaltia : anàlisi narrativa en l'experiència de càncer 

    Espinàs i Olvera, Laura (Date of defense: 2010-07-12)

    En la present tesi doctoral es presenta, des d'una perspectiva narrativa i socioconstruccionista, una aproximació a l'estudi de l'experiència de malaltia en càncer a partir del treball amb relats narrats. Es realitza una ...

    Identificació de les necessitats de les dones diagnosticades de càncer de mama en diferents períodes des del diagnòstic de la malaltia 

    Jurado Pérez, Rocío (Date of defense: 2016-01-15)

    To carry out an appropriate nursing intervention in women diagnosed of breast cancer, it is necessary to know the needs of this group and to have instruments that allow a reliable and valid assessment of their needs. The ...

    Impacte clínic del càlcul de la dosi absorbida en radioteràpia externa mitjançant un nou algorisme basat en la solució de l'equació de Boltzmann 

    Muñoz Montplet, Carles (Date of defense: 2022-03-01)

    The algorithm for calculating absorbed dose in external radiotherapy Acuros XB (AXB), based on the solution of the Boltzmann equation, has shown to achieve a higher level of accuracy than the preceding convolution/superposition ...

    El Inhibidor de carboxipeptidasa de patata (PCI): un antagonista del EGF con actividad antitumoral 

    Blanco Aparicio, Carmen (Date of defense: 1998-07-17)

    In this work we report that potato carboxypeptidase inhibitor suppresses the growth of several human and mouse pancreatic adenocarcinoma cell lines. The inhibitor also reduces the growth of solid tumors obtained by ...

    Inhibition of sialyltransferases in pancreatic cancer: effects on the EGFR pathway and on the tumour phenotype 

    Miró Domènech, Laura (Date of defense: 2023-01-13)

    Pancreatic ductal adenocarcinoma (PDA) presents a dismal prognosis mainly due to its delayed diagnosis, its aggressiveness, and resistance to existing therapies. Aberrant glycosylation and, in particular, the overexpression ...

    Métodos de estadística espacial para evaluar la influencia de factores medioambientales sobre la incidencia y mortalidad por cáncer 

    Lertxundi Manterola, Aitana (Date of defense: 2007-02-16)

    Los objetivos de la tesis son:<br/>1.- Estudiar la relación entre la incidencia y mortalidad por cáncer y los factores medioambientales, en particular la contaminación atmosférica, controlando por factores socioeconómicos.<br/>2.- ...