Now showing items 1-20 of 50
Ferreira dos Santos, Maria do Carmo (Date of defense: 2020-10-26)
Breakthrough cancer pain due to its characteristics, fast onset, short duration and high severity implies a significant reduction in the quality of 2/2 life perceived by affected persons. For this reason, breakthrough ...
Guerrero Barrado, Pedro Enrique (Date of defense: 2020-07-29)
Pancreatic Ductal Adenocarcinoma (PDA), the most common pancreatic cancer, remains one of the most lethal tumor types, with extremely low survival rates due to late diagnosis and resistance to standard therapies. Expression ...
Carrion-Salip, Dolors (Date of defense: 2014-09-17)
Most current chemotherapeutic agents are of limited use due to their side effects and the resistance to treatment that tumour cells develop. In this thesis, we have contributed to the knowledge of these limitations through ...
Oyarzo Sardiña, Juan Fernando (Date of defense: 2020-12-16)
The female sports, both in high performance and in regular physical activity, is impacted by physical, psychological and social characteristics. However, there are still few studies that analyze injuries, pain and training ...
Panosa Roqueta, Clara (Date of defense: 2015-12-14)
The members of the epidermal growth factor (EGF) / ErbB family are prime targets for cancer therapy. However, the therapeutic efficiency of the existing anti-ErbB agents is limited. Thus, identifying new molecules that ...
Rastgoo, Mojdeh (Date of defense: 2016-06-13)
Malignant melanoma is the deadliest of skin cancers and causes the majority of deaths in comparison to other skin-related malignancies. Yet it is the most treatable type of cancer, thanks to its early diagnosis. Subsequently, ...
Korotkov, Konstantin (Date of defense: 2014-07-08)
Malignant melanoma is the rarest and deadliest of skin cancers causing three times more deaths than all other skin-related malignancies combined. Fortunately, in its early stages, it is completely curable, making a total ...
Cufí González, Sílvia (Date of defense: 2015-05-22)
Aquest és el primer informe que demostra que l'autofàgia està mecànicament vinculat al manteniment de les cèl•lules tumorals que expressen alts nivells de CD44 i baixos nivells de CD24, que són típics de les cèl•lules mare ...
Gimeno Cajal, Alfredo Eduardo (Date of defense: 2022-04-22)
Magnetic resonance imaging (MRI) is essential in the management of patients with glioblastoma, providing useful information for diagnosis, prognosis, and therapeutic planning. Although some presurgical and postsurgical ...
Puig Vives, Montserrat (Date of defense: 2015-02-24)
The aim of this thesis is to carry out an in-depth study of various aspects of breast cancer epidemiology. Firstly, we have confirmed that DCIS incidence in Girona has increased over recent decades. Proportions of ...
Díaz Santa, Johana Alejandra (Date of defense: 2022-12-16)
Acute myeloid leukemia (AML) is adults' most common acute leukemia. Prognostic factors influencing treatment response and patient survival are diverse, the most relevant being those associated with specific cytogenetic and ...
Tortajada Giménez, Meritxell (Date of defense: 2017-07-17)
This thesis is focused on the automatic detection of masses in FFDM images by using case-level information which includes bilateral, temporal and/or ipsilateral information. As a first step, FFDM images are preprocessed ...
Carbó Bagué, Anna (Date of defense: 2023-03-27)
In this doctoral thesis, the epidemiology of cutaneous and mucosal melanoma is analyzed, as well as its molecular profile to provide new knowledge on a population basis in the province of Girona. The cancer registry of ...
Agarwal, Richa (Date of defense: 2019-09-26)
In the field of breast cancer imaging, traditional Computer Aided Detection (CAD) systems were designed using limited computing resources and used scanned films (poor image quality), resulting in less robust application ...
Pons Rodríguez, Gerard (Date of defense: 2014-01-21)
This thesis deals with the detection, segmentation and classification of lesions on sonography. The contribution of the thesis is the development of a new Computer-Aided Diagnosis (CAD) framework capable of detecting, ...
Massich i Vall, Joan (Date of defense: 2013-12-04)
This thesis analyses the current strategies to segment breast lesions in Ultra-Sound (US) data and proposes a fully automatic methodology for generating accurate segmentations of breast lesions in US data with low false ...
Farrés Coll, Ramon (Date of defense: 2023-03-10)
Introduction: Anastomotic leak (AL) is the most feared complication in the postoperative period for patients with rectal cancer. Objectives: To determine the real rate of AL in patients operated on for rectal cancer. ...
Perruca Martínez, Cristina (Date of defense: 2022-03-04)
The lack of knowledge and skills in the care of infants in their first years of life often results in frequent paediatric consultations for banal problems and doubts, which are often a result of a low level of health ...
Rabionet Diaz, Marc (Date of defense: 2021-11-08)
Triple negative breast cancer (TNBC) accounts for 15-20% of the breast cancers and displays an aggressive profile, poor prognosis, high relapse risk and does not have a targeted therapy. In the last years, breast cancer ...
Solans Margalef, Marta (Date of defense: 2019-10-14)
Diet is a key modifiable risk factor for several neoplasms, but evidence for lymphoid malignancies is still inconsistent. Previous epidemiological studies were mostly focused on single dietary components (i.e. nutrients ...