Universitat de Girona
Mostrando ítems 1-20 de 29
En aquesta tesi s'han estudiat les propietats antitumorals d'una variant de la ribonucleasa pancreàtica humana anomenada PE5 que incorpora un senyal de localització nuclear. Aquest estudi mostra que PE5 indueix l'apoptosi ...
Tissue Engineering plays a vital role in tissue construct to repair, maintain or replace tissues. Those tissues can be cultivated in vivo or in vitro using devices such as bioreactors. There are several approaches to ...
L'ús d'esperma criopreservada en la inseminació artificial (IA) d'espècies d'interès productiu permet un major control sanitari i la creació de bancs de germoplasma d'alt valor genètic, entre d'altres avantatges. En el ...
Currently, automatic analyzers based on highly accurate methods can determine hematologic parameters in a fast and reliable way which is important to detect abnormalities in blood cells. In laboratories with a high care ...
El present treball analitza la morfologia espermàtica de l'ejaculat de Sus domesticus, la histologia del conducte epididimari i la qualitat de l'esperma epididimari. El material d'estudi prové de mascles reproductors porcins ...
Minor histocompatibility antigens (mHAgs) are peptides derived from polymorphic intracellular proteins that can be recognized in an allogeneic setting by the donor T-lymphocytes leading to the appearance of graft-versus-host ...
Boar semen is not collected under sterile conditions,so boar ejaculates are commonly contaminated with a broad range of microorganisms, which may affect sperm quality and lead to a low reproductive performance and severe ...
This research work proposes a novel automated and integrated system for the production and in vitro culture of scaffolds, called BioCell Printing. The main goal of the present research work, besides the development of the ...
En aquesta tesi s'ha caracteritzat la ruta d'internalització de l'onconasa, una RNasa citotòxica. Els resultats indiquen que l'onconasa entra a les cèl·lules per la via dependent de clatrina i del complex AP-2. Seguidament ...
This thesis is focused on the application of small constraint-based models to analyze and predict the behavior of wild type and modified strains of Pichia pastoris. The presented work deals with the common limitations that ...
Colorectal Cancer is the main type of cancer in Spain. Up to 90% of the cases are sporadic in nature and its aetiology is still unclear. It is supposed to be a multi-factorial disease, where factors play an important role ...
Triple negative breast cancer (TNBC) accounts for 15-20% of the breast cancers and displays an aggressive profile, poor prognosis, high relapse risk and does not have a targeted therapy. In the last years, breast cancer ...
Les malalties causades per bacteris i fongs són responsables d’importants pèrdues econòmiques en cultius. Es considera que els pèptids antimicrobians, naturals i sintètics, són uns bons candidats per a ser utilitzats com ...
El disseny i la producció de zimògens de ribonucleases que puguin ser específicament activats per la proteasa d’un patogen, constitueix un enginyós mecanisme per controlar la seva activitat enzimàtica i, conseqüentment, ...
The major clinical problem for HER2+ breast cancer target therapies is the acquisition of resistance. The DNA methylation status of the promoter gene region has been described as a common epigenetic alteration for ...
Chromosome abnormalities are one of the most important causes of congenital disorders. The main goal of this research is to give a broad view of the use and evolution of prenatal and postnatal cytogenetic diagnosis in ...
In a small region of the island of Gran Canaria, 11 cases of sudden cardiac death (SCD) were registered in emotional or physical stress situations in young individuals between 1994 and 2007 in four seemingly unrelated ...
This thesis is about challenges that currently concern in vitro production (IVP), sex determination procedures and sex-related survival of in vitro-produced porcine embryos. Specifically, the current thesis develops a new ...
Pancreatic ductal adenocarcinoma (PDA) presents a dismal prognosis mainly due to its delayed diagnosis, its aggressiveness, and resistance to existing therapies. Aberrant glycosylation and, in particular, the overexpression ...
S'estudia la histologia normal de la paret corporal d'Hirudo medicinalis i els canvis morfogenètics que es donen durant el procés de cicatrització de ferides per incisió, cauterització i nitrat de plata.<br/>El procés de ...
