Universitat de Girona
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Breakthrough cancer pain due to its characteristics, fast onset, short duration and high severity implies a significant reduction in the quality of 2/2 life perceived by affected persons. For this reason, breakthrough ...
Pancreatic Ductal Adenocarcinoma (PDA), the most common pancreatic cancer, remains one of the most lethal tumor types, with extremely low survival rates due to late diagnosis and resistance to standard therapies. Expression ...
Most current chemotherapeutic agents are of limited use due to their side effects and the resistance to treatment that tumour cells develop. In this thesis, we have contributed to the knowledge of these limitations through ...
The female sports, both in high performance and in regular physical activity, is impacted by physical, psychological and social characteristics. However, there are still few studies that analyze injuries, pain and training ...
The members of the epidermal growth factor (EGF) / ErbB family are prime targets for cancer therapy. However, the therapeutic efficiency of the existing anti-ErbB agents is limited. Thus, identifying new molecules that ...
Malignant melanoma is the deadliest of skin cancers and causes the majority of deaths in comparison to other skin-related malignancies. Yet it is the most treatable type of cancer, thanks to its early diagnosis. Subsequently, ...
Malignant melanoma is the rarest and deadliest of skin cancers causing three times more deaths than all other skin-related malignancies combined. Fortunately, in its early stages, it is completely curable, making a total ...
Aquest és el primer informe que demostra que l'autofàgia està mecànicament vinculat al manteniment de les cèl•lules tumorals que expressen alts nivells de CD44 i baixos nivells de CD24, que són típics de les cèl•lules mare ...
Magnetic resonance imaging (MRI) is essential in the management of patients with glioblastoma, providing useful information for diagnosis, prognosis, and therapeutic planning. Although some presurgical and postsurgical ...
The aim of this thesis is to carry out an in-depth study of various aspects of breast cancer epidemiology. Firstly, we have confirmed that DCIS incidence in Girona has increased over recent decades. Proportions of ...
Acute myeloid leukemia (AML) is adults' most common acute leukemia. Prognostic factors influencing treatment response and patient survival are diverse, the most relevant being those associated with specific cytogenetic and ...
This thesis is focused on the automatic detection of masses in FFDM images by using case-level information which includes bilateral, temporal and/or ipsilateral information. As a first step, FFDM images are preprocessed ...
In this doctoral thesis, the epidemiology of cutaneous and mucosal melanoma is analyzed, as well as its molecular profile to provide new knowledge on a population basis in the province of Girona. The cancer registry of ...
In the field of breast cancer imaging, traditional Computer Aided Detection (CAD) systems were designed using limited computing resources and used scanned films (poor image quality), resulting in less robust application ...
This thesis deals with the detection, segmentation and classification of lesions on sonography. The contribution of the thesis is the development of a new Computer-Aided Diagnosis (CAD) framework capable of detecting, ...
This thesis analyses the current strategies to segment breast lesions in Ultra-Sound (US) data and proposes a fully automatic methodology for generating accurate segmentations of breast lesions in US data with low false ...
Introduction: Anastomotic leak (AL) is the most feared complication in the postoperative period for patients with rectal cancer. Objectives: To determine the real rate of AL in patients operated on for rectal cancer. ...
The lack of knowledge and skills in the care of infants in their first years of life often results in frequent paediatric consultations for banal problems and doubts, which are often a result of a low level of health ...
Triple negative breast cancer (TNBC) accounts for 15-20% of the breast cancers and displays an aggressive profile, poor prognosis, high relapse risk and does not have a targeted therapy. In the last years, breast cancer ...
Diet is a key modifiable risk factor for several neoplasms, but evidence for lymphoid malignancies is still inconsistent. Previous epidemiological studies were mostly focused on single dietary components (i.e. nutrients ...
