Mostrando ítems 41-50 de 59
Guindo Martínez, Marta (Fecha de defensa: 2019-12-18)
Genome-wide association studies (GWAS) have been proven useful for identifying thousands of associations between genetic variants and human complex diseases and traits. However, the identified loci ...
Pertsovskaya, Inna (Fecha de defensa: 2014-06-25)
Systems Biology opens new frontiers in the studies of complex diseases such as Multiple Sclerosis (MS). The questions that couldn’t be addressed before due to lack of understanding and methodological ...
Lema Amado, Rafael (Fecha de defensa: 2020-11-19)
The connection between DNA folding and chromatin conformation has been much studied but the relation between the modulation of chromatin conformation and biological processes such as DNA damage, cell ...
Buitrago Ospina, Diana Camila (Fecha de defensa: 2019-12-16)
Understanding the connection between DNA organization in the nucleus, and cell functioning is one of the most intriguing problems in biology. Although many interdisciplinary efforts have been developed ...
Remesar Betlloch, Xavier (Fecha de defensa: 1979-01-01)
Se han estudiado los niveles de aminoácidos individuales (lactato, glucosa, glicerol, etc.) en plasma y actividad de GLU-deshidrogenasa, ASP-transaminasa, ALA-transaminasa, TYR-transaminasa, ...
Lobón García, Irene (Fecha de defensa: 2019-07-26)
Somatic mutations are those that arise after the zygote is formed and are therefore inherited by a fraction of the cells of an individual. Their relevance in certain skin diseases has been known for ...
Arranz Villacañas, Juan (Fecha de defensa: 2016-12-16)
DYRK1A es un gen del cromosoma 21 humano que codifica para una proteína quinasa constitutivamente activa que fosforila a sustratos que son clave en el desarrollo del cerebro. La proteína DYRK1A regula ...
Meléndez Esteban, Elena (Fecha de defensa: 2022-03-24)
The ectopic expression of transcription factors Oct4, Sox2, Klf4 and Myc (OSKM) enables the conversion of differentiated cells into pluripotent stem cells, a process known as “reprogramming”. Methods ...
Sfriso, Pedro (Fecha de defensa: 2016-03-18)
Sequence, structure and dynamics are an indivisible tandem to understand protein function. Luckily, evolution imposed a hierarchical rational between that facilitates the analysis: dynamics are encoded ...
López Ferrando, Víctor (Fecha de defensa: 2019-12-11)
Single amino acid variants (SAVs) are one of the main causes of Mendelian disorders, and play an important role in the development of many complex diseases. At the same time, they are the most common ...