Now showing items 6-25 of 37
Alvarez Periel, Elena (Date of defense: 2018-07-06)
Huntington’s disease (HD) is a neurodegenerative disorder caused by an autosomic mutation on the Huntingtin (HTT) coding gene. HD is mainly characterized by the appearance of motor symptoms or choreas, which are associated ...
Duran Güell, Marta (Date of defense: 2023-04-12)
[eng] Albumin exerts pleiotropic actions beyond its oncotic power, which include binding, transport and detoxification of endogenous and exogenous molecules, antioxidant activity and the modulation of immune and inflammatory ...
Durán Rodríguez, Rodrigo (Date of defense: 2022-01-28)
Partint dels resultats previs obtinguts per aquest grup d’investigació, es planteja la següent hipòtesi de treball: “La proteïna p27 és un regulador de la via de Notch. Aquesta regulació es realitzaria, principalment, ...
Augé Fradera, Josep Maria (Date of defense: 2017-05-26)
INTRODUCCIÓ: A nivell mundial el càncer de còlon i recte (CCR) és el segon i el tercer en freqüència en homes i en dones, respectivament. La seva història natural és coneguda, se sap que habitualment es desenvolupa a ...
García Díaz, Roberto (Date of defense: 2023-05-26)
[spa] Debido a la importancia de la modulación del NMDAR, en el grupo de investigación de proteínas (GRIP) se han diseñado una serie de péptidos derivados de la Conantokina-G (Con-G), un péptido antagonista de los NMDARs, ...
Suelves Caballol, Núria (Date of defense: 2018-07-23)
Huntington’s disease (HD) is a rare genetic disorder caused by an aberrant expansion of a CAG trinucleotide in the huntingtin gene (Htt). The neuropathology of the disease is characterized by progressive neuronal dysfunction ...
Llanes Velasco, Julia (Date of defense: 2020-09-16)
A Schizosaccharomyces pombe, la citocinesi està mediada per l’assemblatge i la constricció de l’anell contràctil d’actomiosiona. Pertorbacions petites en aquesta estructura activen un conjunt de mecanismes de control que ...
Abuasaker, Baraa (Date of defense: 2024-06-14)
[eng] INTRODUCTION: The Kirsten rat sarcoma oncogene (KRAS) homologue stands out as a prominent oncogene, distinguished by its notably elevated mutation rate compared to other oncogenes. This genetic anomaly is intricately ...
Rodríguez Urgellés, Ened (Date of defense: 2022-01-20)
Huntington’s Disease (HD) is an autosomal dominant inherited neurodegenerative disorder characterized by motor, psychiatric, and cognitive manifestations. The disease is caused by an unstable expansion of the CAG trinucleotide ...
Ligero Hernández, Marta (Date of defense: 2024-03-15)
[eng] HYPOTHESIS: Precision oncology has revolutionized the landscape of cancer treatment. Emerging therapeu- tic approaches, such as immunotherapy or anti-angiogenic agents, have exhibited remarkable outcomes in solid ...
Andrés Bilbé, Alba (Date of defense: 2020-11-13)
[cat] TRESK (K2P18.1) és un canal de potassi de fuga que s’expressa en algunes subpoblacions de neurones sensorials, on modula el potencial de membrana en repòs, la descàrrega de potencial d’acció i l’excitabilitat neuronal. ...
Siegert, Anna-Maria Elisa (Date of defense: 2017-10-20)
Marfan Syndrome (MFS) is a rare, autosomal dominant disorder of the connective tissue that affects between 1.5 and 17.2 in 100.000 live births. MFS is caused by mutations in the extracellular matrix (ECM) glycoprotein ...
Proaño Pérez, Elizabeth (Date of defense: 2022-11-30)
[eng] KIT (CD117) is a tyrosine kinase receptor expressed in hematopoietic progenitors, melanocytes, germ cells, mast cells, and interstitial cells of Cajal (ICC) of the digestive tract. KIT gain-of-function mutations have ...
Romero Moya, Damià (Date of defense: 2017-01-16)
Homeostasis of the hematopoietic stem/progenitor cell pool relies on a finely tuned balance between self-renewal, differentiation and proliferation. Recent work has revealed the importance of mitochondria during stem cell ...
López Molina, Laura (Date of defense: 2022-06-17)
[spa] La enfermedad de Huntington (EH) es una enfermedad neurodegenerativa hereditaria causada por la mutación de la huntingtina (mHtt) que ocasiona síntomas motores, cognitivos y psiquiátricos. La característica ...
Solaguren-Beascoa Negre, Maria (Date of defense: 2024-02-02)
[eng] The hypothesis underlying the AMBAR study research seeks to evaluate the clinical efficacy of PE, in combination with albumin and intravenous immunoglobulin replacement (IVIG), as a treatment for Alzheimer's disease ...
Youssif, Catrin (Date of defense: 2017-10-27)
Chronic inflammation is a hallmark of colon cancer, and patients with inflammatory bowel disease are prone to developing colon tumors. In recent years, many efforts have been devoted to characterize the interplay between ...
Miguez Cabello, Federico (Date of defense: 2021-02-09)
[eng] Speaking metaphorically, the human nervous system is a complex ensemble of millions of parts operating together one with another. For this reason, each part is fundamental for the correct function of the whole system. ...
Soler-Ventura, Ada (Date of defense: 2021-03-05)
L’aplicació de tècniques d’alt rendiment, com la transcriptòmica i la proteòmica, en l’estudi de l’espermatozoide humà, ha permès obtenir grans avenços en la coneixença de la seva composició i funció normal, així com ...
Unzueta Payeras, Fernando (Date of defense: 2023-07-28)
[cat] El nostre laboratori està centrat en l’estudi de la resposta a l’estrès replicatiu, ja que aquest estrès està relacionat amb la tumorigènesi i la seva resposta és un mecanisme fonamental per preservar l’estabilitat ...