Ara mostrant els elements 21-40 de 116
Bustos Araya, Marta Eduviges (Data de defensa: 2023-02-24)
[eng] The interest of this work was to manufacture solid lipid nanoparticles that serve as a vehicle for biomolecules, specifically Chondroitin sulfate and pEGFP plasmid DNA. In the experimental part, the reagents and ...
Caballero Muñoz, Iracema (Data de defensa: 2021-03-26)
Pathologies that result in highly modulated intensities in macromolecular crystal structures pose a challenge for structure solution. To address this issue two studies have been performed: a theoretical study of one of ...
Camps i Fajol, Cristina (Data de defensa: 2022-12-19)
[eng] Cancer is the second leading cause of death globally. The gold standard for cancer has historically been surgery, radiotherapy and chemotherapy. Although the efficacy of chemotherapy has been broadly confirmed, drug ...
Zuazo Gaztelu, Iratxe (Data de defensa: 2018-11-23)
Tumor progression is a complex conundrum of events that involve not only tumor cells, but also their surrounding microenvironment. Accounting to the natural dependency of tumors on angiogenesis, its therapeutic targeting ...
Negrete Sánchez, Elsa N. (Data de defensa: 2019-10-11)
Actualmente, el 80% de los injertos hepático proceden de donantes con muerte cerebral. Sin embargo, la muerte cerebral reduce la tolerancia de los injertos hepáticos a la lesión por isquemia/reperfusión y contrarresta los ...
Oliva Lorenzo, Laia (Data de defensa: 2019-06-27)
El sobrepeso y la obesidad son condiciones patológicas, con una prevalencia elevada, que están consideradas como una de las principales causas de mortalidad. Los factores genéticos, y especialmente, los factores ambientales ...
Bustillos Ortiz, Alcides Alberto (Data de defensa: 2017-09-26)
La histona H1 se une al nucleosoma, situándose en la base, cerca de los sitios de entrada y salida del DNA, siendo una de sus principales funciones descritas, el mantenimiento de una estructura estable y condensada de la ...
Riaño Canalias, Ferran (Data de defensa: 2017-09-29)
Ribosome biogenesis is one of the most energy consuming anabolic processes in a cell, required for the generation of the translational machinery to grow and proliferate. Moreover, this process necessitates the coordination ...
Kopper, Klaudia Lilla (Data de defensa: 2021-11-26)
This thesis has been developed in the framework of the European FoodSmartphone project with the objective to develop user-friendly smartphone-connected electrochemical immunosensors for pesticide residue detection in ...
Calle Fabregat, Carlos de la (Data de defensa: 2022-03-15)
OBJECTIVE: Identifying predictive biomarkers at early stages of undifferentiated arthritis (UA) is crucial for starting appropriate therapies to avoid poor outcomes. Monocytes and macrophages, largely associated with ...
Illanes Vicioso, Ramiro (Data de defensa: 2023-11-10)
[spa] El desarrollo de mi tesis doctoral abarca el análisis estructural y en solución de dos proteínas mitocondriales: la isoforma 1 del Factor de Transcripción A Mitocondrial (TFAM) y el dominio N-terminal de la isoforma ...
Escudero Bravo, Paloma (Data de defensa: 2021-07-15)
Los transportadores heteroméricos de aminoácidos (HAT) se encuentran compuestos por una subunidad pesada que dirige el tráfico del transportador a la membrana plasmática y la subunidad ligera que posee la actividad catalítica. ...
Crespo Puig, Anna (Data de defensa: 2017-04-27)
Les ribonucleotidil reductases (RNR) són metal·loenzims essencials per la vida que catalitzen la reducció dels ribonucleòtids (NTPs) a desoxiribonucleòtids (dNTPs), per tant, les RNRs són enzims necessaris per a l’obtenció ...
Simón Extremera, Pilar (Data de defensa: 2017-05-12)
El carcinoma escamoso (SCC) es el segundo tumor de piel más frecuente en humanos caucásicos. Estudios recientes demuestran que el crecimiento tumoral es mantenido por una población de células tumorales, las células madre ...
Rafels Ybern, Àlbert (Data de defensa: 2018-07-17)
Inosine is a guanosine analogue that when is found at the wobble position of the tRNAs (I34) expands its codon recognition capability. Inosine can wobble pair with cytosine, adenosine and uridine. Because inosine is not ...
Ramírez Pedraza, Marta (Data de defensa: 2020-12-18)
El carcinoma hepatocel·lular (HCC) és la segona causa de mort relacionada amb càncer i té avui en dia opcions terapèutiques molt limitades. Tot i que el HCC s’acostuma a estudiar en estats de malaltia hepàtica molt avançats, ...
Atanasov, Kostadin Evgeniev (Data de defensa: 2019-05-14)
Arabidopsis thaliana is a small ruderal weed with prominent north-hemisphere distribution. It has an autogamous style of reproduction, whereas about 3% of the natural population can exhibit outcrosses. Some of these ...
Zapata Garin, Claire-Alix (Data de defensa: 2018-06-01)
Glycogen is a branched polysaccharide that serves as an intracellular store of glucose that can be mobilized to maintain homeostasis or to fuel cellular processes. Glycogen is synthesized by glycogen synthase, which is ...
Izquierdo Villalba, Ismael (Data de defensa: 2020-01-17)
G proteins transduce a myriad of signals from receptors at the plasma membrane. Recent reports point to a novel localization of G proteins at the mitochondria and other endomembranes where they regulate the physiology of ...
Lewis, Michael (Data de defensa: 2022-11-11)
[eng] Transcriptional regulation is a multifaceted and fundamental process, which underpins normal physiology, and its dysregulation is associated to numerous pathologies. Using two inherently different transcriptional ...