Gomes, Tiago Lopes (Date of defense: 2019-11-05)
Signal transduction pathways are essential mechanisms that cells use to perform a myriad of biological processes that when aberrant, can cause serious diseases. Understanding the molecular basis of these ...
Cuppari, Anna (Date of defense: 2016-12-21)
The mitochondrial transcription factor A, TFAM, has a dual function in the organelle: it activates mitochondrial DNA transcription by binding to the HSP and LSP promoters, while in higher concentrations ...
Andreu Solduga, Franc (Date of defense: 2017-09-29)
The calcineurin inhibitor Tacrolimus (Tac) is used to prevent acute rejection after renal transplant. Unfortunately, the clinical use of Tac is complicated by its considerable toxicity, narrow therapeutic ...
Carola, Giulia (Date of defense: 2019-07-26)
Dopaminergic neurons (DAn) were efficiently differentiated from 6 different iPSC lines derived from a 2 control, 3 PD lines, and an isogenic PD line. We characterize the culture at different time point ...
Vidal Miñano, Pedro Jesús (Date of defense: 2020-09-07)
En Ia levadura de gemación el tamaño celular en START o tamaño crítico está determinado por Ia velocidad de crecimiento en G1. Durante esta fase, Saccharomyces cerevisiae presenta una disminución ...
Ortiz Hernández, Raül (Date of defense: 2017-09-06)
La regulació local de la síntesi proteica permet a la neurona respondre ràpidament a senyals sinàptiques, és un element fonamental de la plasticitat sinàptica i està alterat en moltes patologies neuronals. ...
Aznar Lou, Ignacio (Date of defense: 2017-06-29)
La no iniciación es un comportamiento que se caracteriza por no empezar aquellos tratamientos farmacológicos prescritos por primera vez. Este comportamiento puede estar influenciado por distintos factores ...
Quintairos Domenech, Luis (Date of defense: 2021-07-08)
Despite advances in immunosuppression, allograft rejection and clinical outcomes remain a challenge in solid organ transplantation. Currently, the immunosuppressive treatment’s individual adjustment is ...
Robert i Sabaté, Laia (Date of defense: 2020-07-09)
La comunicació en salut i la millora de l’alfabetització per a la salut són aspectes clau en les polítiques sanitàries. L’èxit d’un tractament farmacològic no només depèn de l’eficàcia del medicament ...
López Yerena, Anallely (Date of defense: 2021-09-28)
The health promoting attributes associated with following a traditional Mediterranean diet have been reviewed extensively. The principal source of dietary fat in the Mediterranean diet is Extra virgin ...