Torres Ferraz, Rosa (Date of defense: 2018-12-20)
Actualment no existeix cap medicament aprovat pel tractament de la Síndrome de l’Ovari Poliquístic (PCOS), un dels desordres endocrins més freqüent en dones en edat reproductiva, amb una prevalença ...
Dumaze, Anaëlle (Date of defense: 2023-11-08)
[eng] My thesis was part of a collaborative project at the interface of neuropharmacology and medicinal chemistry that aimed to better understand the neuromodulation mechanisms associated with Alzheimer’s ...
González Álamos, María (Date of defense: 2023-11-21)
[eng] The vault particle, with a mass of 10 MDa and dimensions of 70 nm x 40 nm x 40 nm, is the largest ribonucleoprotein described in the eukaryotic kingdom. The vault shell is organized in two identical ...
Iannizzotto, Flavia (Date of defense: 2023-12-01)
[eng] MYC dysregulation is the most common alteration in cancers, driving several cellular processes that cooperatively promote aberrant cell growth and proliferation. Among them, the induction of protein ...
Guercetti, Julian (Date of defense: 2023-10-25)
[eng] The current doctoral thesis titled “Microarray Strategies for Multiplexed Immunochemical Analysis” was carried out in the context of two research projects, expecting to develop multiplexed ...
Schmitz, Claus-A. (Date of defense: 2023-04-26)
[eng] We investigated the structure function relationship of PorX by combined biophysical experiments and enzymatic assays. As a regulator of the type 9 secretion system (T9SS) of the human pathogen ...
Illanes Vicioso, Ramiro (Date of defense: 2023-11-10)
[spa] El desarrollo de mi tesis doctoral abarca el análisis estructural y en solución de dos proteínas mitocondriales: la isoforma 1 del Factor de Transcripción A Mitocondrial (TFAM) y el dominio ...
Marzal Martí, Berta (Date of defense: 2023-12-18)
[spa] El cáncer de mama es el tumor más frecuentemente diagnosticado en mujeres y entre sus diversos subtipos, en esta tesis, nos centraremos particularmente en el cáncer de mama HER2+. Esta patología ...
Pérez Matas, Edgar (Date of defense: 2023-12-19)
[eng] Plant specialized metabolism is the source of a wide range of bioactive compounds, some of which with relevant pharmacological properties. Nowadays, cancer is one of the main causes of mortality ...
Murillo Villuendas, Ester (Date of defense: 2023-10-20)
[eng] Polyamines are small polycationic molecules that contain amino groups and are found in all living organisms. This study is aimed at acquiring a comprehensive understanding of the diverse roles of ...