Browsing Departament de Biociències by Subject "57"

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    Exploring the Drug-Adverse Reaction and Drug-Target Landscape through Networks, Statistics and Machine Learning Approaches 

    Galletti, Cristiano (Date of defense: 2022-10-10)

    The amount of attrition in drug discovery, particularly at advanced stages, is quite high due to unexpected adverse drug reactions (ADRs) generated by drug candidates; hence, being able to anticipate unexpected reactions ...

    The Role of N-Glycosylation of Integrin α5β1: From Molecular Spatiotemporal Behavior to Cellular Function 

    Masó Orriols, Sergi (Date of defense: 2025-03-28)

    Les integrines són receptors transmembrana que regulen processos cel·lulars com la migració i la proliferació. Aquesta tesi estudia la integrina α5β1 i el paper de les N-glicosilacions en la seva funcionalitat. Es van ...