Now showing items 5-24 of 51
Ricco Pacheco, Natalia (Date of defense: 2013-07-23)
La ciclina Cln3 es un activador crítico de START, cuya sobreexpresión provoca células de menor tamaño que progresan rápidamente por el ciclo celular, mientras que su deleción induce un mayor tamaño de las células y retrasa ...
Carballar Ruiz, María de los Reyes (Date of defense: 2021-02-25)
DNA double-strand breaks (DSBs) are considered the most deleterious lesions of DNA and they are repaired by means of two main mechanisms: homologous recombination (HR) and non-homologous endjoining (NHEJ). These mechanisms ...
Romero Cortadellas, Lídia (Date of defense: 2023-09-22)
Iron is a biometal involved in many physiological processes that are essential for life. Iron metabolism is a complex and tightly regulated process both at the systemic and cellular level. Proper iron homeostasis relies ...
Hernández Ortega, Sara (Date of defense: 2014-07-18)
El control del ciclo celular está altamente regulado mediante diferentes CDKs asociadas a ciclinas. En Saccharomyces cerevisiae, la CDK esencial Cdc28 es la que regula mayoritariamente este proceso. En la fase G1 del ciclo ...
Miralpeix Monclús, Cristina (Date of defense: 2019-12-04)
Obesity prevalence in worldwide population is increasing every day due to an imbalance between the energy intake and the energy expenditure. Rich-caloric food is highly palatable and easily accessible, whereas sedentary ...
Fosch Masllovet, Anna (Date of defense: 2022-07-28)
Obesity has become a pandemic disease in the last 40 years. The WHO estimates that the population with overweight has nearly tripled since 1975, and the tendency is still growing. These data have an impact on health and ...
Reguera Moreno, Ana Cristina (Date of defense: 2023-12-04)
El sistema endolisosomal juga un paper crític en la funció neuronal i ha emergit com a un potencial objectiu per al tractament de diverses malalties neuronals, com els trastorns neurodegeneratius i fins i tot l'obesitat. ...
Casas Prat, María (Date of defense: 2019-11-18)
Carnitine palmitoyltransferase 1C (CPT1C) is the brain-specific isoform of the CPT1 family which is located at the endoplasmic reticulum (ER) of neurons and exhibits low catalytic activity, but still maintains the capacity ...
Amo Mora, Isabel (Date of defense: 2023-09-09)
La creciente prevalencia de enfermedades mentales y cronicidad orgánica genera una comorbilidad con impacto en la salud, calidad de vida y eficiencia de los modelos de atención. Se necesita un enfoque multidisciplinario ...
Sarrias Giménez, Ana (Date of defense: 2023-07-19)
Nombre / Nom / Name Ana Apellidos / Cognoms / Surname Sarrias Giménez Dirección de correo electrónico / Adreça de correu electrònic / email address (opcional / optional) anasargim@gmail.com Departamento / Departament ...
García-Chica, Jesús (Date of defense: 2023-12-01)
Brain lipid metabolism has a key role in many physiological processes, and its malfunction is associated with a plethora of diseases, such as obesity and glioblastoma multiforme (GBM). Carnitine palmitoyl transferase 1A ...
Merino Gómez, María (Date of defense: 2023-04-21)
The field of tissue engineering relies on the use of biomaterials as scaffolds for tissue and organ regeneration. If properly designed, these scaffolds can mimic the in vivo microenvironment while also providing initial ...
Rodríguez González, Raquel (Date of defense: 2023-02-07)
The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body cannot regenerate large ...
Bru Rullo, Samuel (Date of defense: 2015-07-20)
Throughout its lifespan, eukaryotic cells steadily consume free cytoplasmic orthophosphate to produce phospholipids and mRNA. However, during DNA synthesis, in a matter of minutes, cells require large amount of phosphate ...
Masip Sales, Núria (Date of defense: 2022-01-27)
Fa quasi 40 anys del descobriment de les ciclines, les proteïnes oscil·lants tradicionalment dividies en dos grups, “cicle cel·lular” i “ciclines transcripcionals”, que duen a terme els seus rols juntament amb la seva ...
Pérez - Martín, Hipólito (Date of defense: 2023-11-17)
El tabaquismo es reconocido a nivel global como un factor de riesgo significativo para la salud pública y una de las principales causas de muertes prevenibles. España ha implementado políticas de control del tabaco con el ...
Lidón Moyano, Cristina (Date of defense: 2017-10-06)
In Spain, two smoke-free laws have been passed after the approval of the FCTC. In 2005, it came into effect a smoke-free legislation (Law 28/2005). This law was a great advance for public health in Spain; however, it was ...
Navarro Martínez, Lourdes (Date of defense: 2017-09-29)
Las proteínas TCF7L2 (transcription factor 7-like 2) son un conjunto de factores de transcripción que participan en la vía Wnt y son responsables, entre otras funciones, del mantenimiento de las células madre y la formación ...
Lamarca Dams, Aloa (Date of defense: 2013-09-13)
Peripheral neuropaties are one of the major complications of the Peripheral Nervous System. Depsite the big importance of those pathologies, less drugs are effective for their treatment, and most of the prescribed drugs ...
Díez Deustua, Patricia (Date of defense: 2015-12-02)
En el presente trabajo revisamos las diferentes variables que han sido asociadas al perdón. Son muchos los factores que influyen en que dicho proceso se lleve a cabo o no. Estudios previos han analizado la importancia ...