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Now showing items 5845-5864 of 41723
Chemical and dynamical analysis of Open Clusters in the context of the Milky Way disc
This thesis has as a main purpose the determination of the chemical composition of Open Clusters for the study of the chemical gradients in the Galactic disc with: Galactocentric radius, position above the plane, and ...
Chemical and ecotoxicological assessment of microplastics and emerging risks in the coastal environments
In recent decades, global plastics production and consumption have continued to increase. Although many policy strategies on waste prevention and recycling have been implemented, much of the plastic waste is dispersed in ...
Chemical and enzymatic valorization of polyols from biomass
En les últimes dècades han augmentat els problemes derivats de la sobreproducció i acumulació de residus de la industria, així com els problemes mediambientals i la disminució de fonts de matèries primeres. En aquest sentit, ...
Chemical and microbial ecology of thc demosponge Aplysina aerophoba = Ecología química y microbiana de la demosponja Aplysina aerophoba
Phylum Porifera (Grant, 1836) are sessile metazoans with a differentiated inhalant and exhalant aquiferous system with external pores. Lacking a tissue grade of construction, sponges can reach two well-differentiated ...
Chemical and synchrotron techniques for the characterization and development of functional foods. Plant biostimulant effects on Se enriching wheat
El seleni és essencial per a la salut humana Les fonts de Se s’obtenen en gran mesura del consum de vegetals, ja que el cos humà no pot sintetitzar de forma eficaç les espècies de Se orgànic assimilables. El selenit i el ...
Chemical approaches to the study of the ceramide synthase activity
Sphingolipids (SLs) are one of the major classes of lipids in eukaryotes. In addition to being essential structural components of cell membranes, SLs also play capital roles as signalling molecules. Ceramides (Cer) are a ...
Chemical design and validation of Ca 2+ -releasing platforms to promote vascularization in tissue regeneration
An insufficient vascularization of the wound site is often the cause of failure in tissue regeneration. The use of cell therapy or growth factors has introduced promising results, nevertheless, they are risky, expensive ...
Chemical Modulation of Identified Hit Compounds as Apoptosis Inhibitors
L’apoptosi és un procés biològic rellevant en moltes malalties. Un punt de regulació d’aquest procés és la formació d’un complex multiproteic anomenat apoptosoma; per tant, aquest complex té un gran interès per al ...
Chemical modulation of the nociceptive receptor TRPV1: Synthetic, biological and computational studies
El canal iònic Receptor Vanil·loide Tipus 1 (sigles en anglès TRPV1) es considera un important integrador de diverses senyals de dolor. D'entre tots els productes que interaccionen amb TRPV1, aquells que bloquegen el senyal ...
Chemical speciation on urinary lithiasis. Image analysis and separation techniques for the study of lithogenesis
La formació de concrecions sòlides al tracte urinari, malaltia que rep el nom de litiasi urinària, és un desordre molt comú arreu del món. La seva taxa de incidència és del 12% a la població mundial, i la de recurrència ...
Chemical tools for the study of sphingolipid metabolism in diseases
[eng] The main goals of this PhD thesis are closely related within the field of CDases and their key role in the regulation of sphingolipid metabolism. Thus, the roles of ACER3 and AC in different human diseases are of ...
Chemical tools to investigate the role of sphingolipids in disease
Sphingolipids (SLs) encompass a large and diverse family of lipids that are essential constituents of cellular membranes. In addition to their structural functions, SLs are also emerging as important signalling molecules ...
Chemical vapor deposition of hexagonal boron nitride and its use in electronic devices
Dielectrics are insulating materials used in many different electronic devices (e.g. capacitors, transistors, barristors), and play an important role in all of them. In fact, the dielectric is probably the most critical ...
Chemically synthesized peptide libraries as a new source of BBB-shuttles. Use of Mass Spectrometry for peptide identification and quantification
The blood-brain barrier (888) is a biological barrier that plays a crucial role protecting the brain from neurotoxic agents and regulating the influx and efflux of molecules required for the correct function of this organ. ...
Chemistry of dawsonites and application in catalysis
La dawsonita es un mineral cristalino hallado generalmente en la naturaleza en forma de hidróxicarbonato de sodio y aluminio, NaAlCO3(OH)2. Además del mineral, se han sintetizado diferentes tipos de dawsonitas variando su ...
Chemoenzymatic Synthesis of Carbohydrates and Derivatives with Engineered D-Fructose-6-Phosphate Aldolase
Biocatalysis is the chemical transformation of organic substrates by enzymes. This is the driving force of some of the oldest transformations known to humans. Nowadays, methods involving biocatalysts are gaining importance ...
Chemoenzymatic synthesis of sugar-related polyhydroxylated compounds, iminocyclitols and their derivatives as glycosidase inhibitors
Section 1 (Introduction) is a comprehensive review of the subjects discussed in this thesis: biocatalysis, aldolases and iminocyclitols. It contains a description of the application of dihydroxyacetone phosphate (DHAP) and ...
Chemoisosterism and its impact on drug polypharmacology
In medicinal chemistry, two chemical fragments are considered bioisosteric if they bind to the same protein environment. Accordingly, looking at the same players from an opposite perspective, two protein environments can ...
Chemomagnetooptically controlled nanomotors for (bio)contaminant removal in water
El objetivo de la tesis es desarrollar nanomotores autónomos de silicio/metal activados fotoelectroquímicamente, explorar y comprender los mecanismos involucrados en el proceso de propulsión y analizar su posible aplicación ...
