Now showing items 2802-2821 of 3232
García López, Roberto (Date of defense: 2018-04-06)
Genome-wide association studies have been very useful tools in the last years to relate genes and diseases. Thereby, single nucleotide polymorphisms have been linked to increased ORMDL3 expression and to different pathologies ...
Touriño Raposo, Clara (Date of defense: 2009-02-17)
La 3,4-metilendioximetamfetamina (MDMA, èxtasi) i el cannabis són dues drogues les quals es consumeixen conjuntament de manera habitual. Malgrat que tots dos compostos presenten propietats reforçant i potencial addictiu, ...
Sánchez Osuna, María (Date of defense: 2014-12-19)
Glioblastoma multiforme, one of the most aggressive and lethal tumors, is characterized by a high apoptosis resistance. This doctoral thesis addresses the biochemical behavior of diverse glioblastoma cells, including primary ...
Moscoso Castro, Maria (Date of defense: 2016-11-28)
The adenosinergic system is a neuromodulatory complex acting on four receptor subtypes with varying distributions throughout the central nervous system. This system contributes to homeostasis and regulates several physiological ...
Calzolari, Simone (Date of defense: 2013-11-15)
Durant el desenvolupament embrionari, els teixits s’especifiquen gradualment fins a que adquireixen un destí final. En els vertebrats el Sistema Nerviós Central (SNC) deriva del tub neural, una estructura embrionària ...
Gutiérrez Martos, Miriam (Date of defense: 2018-06-08)
Drug addiction and several eating disorders share striking similarities in their behavioural patterns triggered by the presence of neuronal alterations in the brain reward circuit. In this Thesis, we investigate the ...
Ill-Raga, Gerard (Date of defense: 2010-09-28)
Nitric oxide (NO) is a neurotransmitter involved in memory processes. Currently, the only recognized physiological signalling pathway controlled by NO is the activation of guanylyl cyclase. In this thesis, we propose an ...
Guix Ràfols, Francesc Xavier (Date of defense: 2009-01-22)
Aquesta tesi demostra que el peroxinitrit produït com a conseqüència del pèptid beta-amiloide (A) contribueix l'augment de la relació A42/A40 que ocorre a la malaltia d'Alzheimer. L'A42 ...
Roset i Huguet, Ramon (Date of defense: 2008-04-04)
The aim of this thesis is the characterization of a protein involved in apoptosis. Our group has identified an early step common to different forms of intrinsic apoptosis stimuli. This step requires de novo synthesis of a ...
Calvo Arnedo, María Isabel (Date of defense: 2012-12-21)
En el laboratorio se utiliza como sistema modelo la levadura Schizosaccaromyces pombe para poder estudiar la respuesta a estrés oxidativo. Las dos rutas principales de respuesta a estrés oxidativo son las del factor de ...
Nicolau Jené, Carles (Date of defense: 2011-02-07)
The goal of synchronization is to align/synchronize the time and frequency scales of all nodes within a network. In industrial applications, synchronization enables simultaneous triggering of distributed events and ...
Bárcena Menéndez, Diego (Date of defense: 2016-10-17)
Una de las preguntas sin resolver en la biologia celular, es como las células mamíferas logran generar patrones estables como organos o seres vivos, en un entorno variable. El concepto matemático del bucle de retreoalimentación, ...
Alsina Burgués, Victòria (Date of defense: 2017-12-21)
Public-private collaboration (PPC) is a phenomenon that has grown spectacularly since the early 1980s. Currently, policy-making processes usually develop in complex networks of public and private institutions, and public ...
Vujovic, Milica (Date of defense: 2021-06-16)
Research has provided relevant advances in evidence-based design for productive learning. For example, in the field of collaborative learning, there is extensive evidence for some key learning design elements, such as ...
Leis Machín, Angela 1974- (Date of defense: 2021-03-18)
Mental disorders have become a major concern in public health, since they are one of the main causes of the overall disease burden worldwide. Depressive disorders are the most common mental illnesses, and they constitute ...
Merino Serrat, Imma (Date of defense: 2013-02-01)
Agnès Varda ha deixat empremtes visibles de la seva subjectivitat en una filmografia desenvolupada pràcticament en sis dècades. El propòsit és abordar el conjunt de l’obra cinematogràfica de Varda rastrejant-hi aquestes ...
Gorigoitía Abbott, Felipe (Date of defense: 2012-10-05)
El presente trabajo trata acerca de la subsanación de los defectos procesales en el procedimiento civil español. Se funda en la tesis de la subsanación como el mecanismo prioritario de eliminación de imperfecciones, por ...
Cepak, Roberta (Date of defense: 2022-01-31)
This study examines the opinions of the Deaf and Hard-of-Hearing and hearers of Spain with regards to the subtitling services currently offered by the Spanish Digital Television, with the aim of integrating them in a list ...
Zacharakis, Alexandros (Date of defense: 2022-10-10)
Succinct non-interactive arguments (snarks) are cryptographic constructions that allow a prover to convince a verifier about the validity of a statement regarding some computation. We consider these objects from the ...
Miranda Mendizabal, Andrea (Date of defense: 2020-03-06)
Suicide is the second leading cause of death among 15- to 29-year-olds. Male youths have higher risk for suicide compared to females, whereas females are at greater risk for suicidal ideation and suicide attempts. Mental ...