Universitat Pompeu Fabra
Now showing items 21-40 of 115
Background and objectives: Middle- and low-income countries face an increasing burden of mortality and disability due to stroke. The aim of this study was to describe the acute care of ischemic stroke, the impact of increased ...
Adolescence is a critical developmental period in which the brain emerges from an immature state to adulthood. This process of brain development is associated to greater cognitive capacity but also to altered emotional ...
Esta tesis estudia dos diferentes dinámicas de intercambio de mensajes entre unidades estocásticas.<br/>Primero, analizamos un conjunto de neuronas estocásticas tipo integración - y - disparo con integración sin pérdidas, ...
Antecedents: No hi ha gaire coneixement sobre el neurodesenvolupament de preescolars i la seva susceptibilitat enfront a factors ambientals. <br/>Objectius: Avaluar les respostes del neurodesenvolupament en nens i les ...
Neuropathic pain is a complex disorder that includes nociceptive, emotional and cognitive manifestations. This work was focused on how inter-individual variability and endogenous opioid system may be associated with these ...
Down syndrome (DS) is the most frequent genetic cause of intellectual disability. It is a multifaceted condition characterized by impairments in cognition, communication, behavior and/or motor skills resulting from ...
Nowadays, most popular therapies for cerebral aneurysms are clipping and coiling. Nonetheless, it is not easy to elucidate which therapeutic option is the most suitable and reliable for a patient-specific aneurysm. To face ...
Down syndrome (DS) is the most common genetic form of intellectual disability and arises from the partial or total trisomy of the Homo Sapiens Autosome 21. The cellular and molecular mechanisms that contribute to memory ...
Risk factors and diagnosis in young people have been little explored, despite brain tumours (BT) is one of the most frequent tumour type in children and adolescents. The purpose of this doctoral thesis is to study 1) the ...
Parkinson’s disease (PD) is the commonest movement disorder and a devastating neurodegenerative condition. Although PD motor symptoms arise from the progressive loss of dopaminergic neurons on the Substantia Nigra, this ...
Brain activity, on every scale, spontaneously fluctuates, thereby exhibiting complex, dynamic interactions that manifest rich synchronization patterns. The past ten years have been dominated by studies intended to further ...
L’origen ambiental i genètic de les diferències individuals en l’aprenentatge de paraules i regles gramaticals és desconegut. Per aquest motiu es van realitzar dos estudis. En el primer, dos grups de bessons, monozigòtics ...
En la present tesi doctoral es va establir i calcular els factors genètics de risc per a la forma tardana de la malaltia d'Alzheimer (MA). Foren analitzats un total de 15 variants gèniques (polimorfismes) ubicats en alguns ...
Estudios genéticos en pacientes sugieren que el gen del receptor tirosina quinasa de la neurotrofina de tipo 3 (NTRK3) podría contribuir en la patología del trastorno de pánico (PAND), un trastorno de ansiedad caracterizado ...
Parkinson’s disease (PD) is an incurable, chronically progressive neurodegenerative disease leading to premature invalidity and death. The locomotor disability of PD patients is mainly rooted in the gradual and insidious ...
El treball presentat en aquesta tesi és un estudi de la diversitat genètica en un conjunt de gens implicats en funcions neurològiques ("Gens cerebrals"). Hom ha examinat vint-i-dos gens implicats en els sistemes de ...
The continuing growth of older age groups worldwide needs an increased understanding of the ageing phenomena. For this reason, the present thesis is aimed at two very important outcomes in the elderly, active ageing (AA) ...
White matter hyperintensities (WMH) have been associated with increased risk and progression of Alzheimer’s disease (AD). However, the range to which this association can be extended to AD risk factors and WMH burden in ...
Chronic pain is a major clinical problem producing huge economic and social burdens. Currently, chronic pain treatment has limited efficacy and significant side effects. One of the reasons of this unmet clinical need is ...
Hypocretin-1 and hypocretin-2, also known as orexin-A and orexin-B, are 2 neuropeptides that are exclusively expressed by a small subset of neurons of the lateral hypothalamic area. Despite their restricted expression ...
