Now showing items 2221-2240 of 3213
Redondo Natella, M. Cristina (Date of defense: 1995-03-06)
EL TRABAJO CONSISTE EN UNA INVESTIGACION METATEORICA ACERCA DE LAS NOCIONES DE RAZON, RAZON PARA LA ACCION Y RAZONAMIENTO PRACTICO Y SU UTILIZACION EN EL ANALISIS DE TRES PROBLEMAS DE LA TEORIA JURIDICA: LA NORMATIVIDAD ...
Shinabe, Naomi (Date of defense: 2014-02-18)
Los libros de texto transmiten de manera bastante uniforme un determinado conocimiento e ideología a una generación entera en un determinado ámbito territorial. Esta tesis pretende analizar, desde la perspectiva crítica, ...
Santaolaya Cesteros, Clara (Date of defense: 2021-01-15)
Este trabajo de investigación se propone realizar un particular recorrido por la historia del cine a través de la figuración de la toma de la calle, es decir, a través del gesto mediante el cual la masa se hace presente y ...
Mac Dougall, Lola (Date of defense: 2016-10-24)
This research looks at the contributions made by some Indian women photographers to the representation of privacy. Indian women photographers have enjoyed a privileged access in their bid to depict privacy, or the quality ...
Guiu Sagarra, Jordi (Date of defense: 2012-11-26)
La regió de l’aorta-gonada-mesonefros (AGM) és el primer nínxol de les cèl·lules mare hematopoètiques. Està descrit que la via de Notch és necessària per generar artèries i cèl·lules mare hematopoètiques. Les cèl·lules ...
Ferrando Martorell, Eva (Date of defense: 2015-11-10)
The activation of Notch1 receptor triggers differential outcomes depending on the upstream activating ligand. This way, Jag1-Notch1 activation promotes endothelial to hematopoietic transition process for the generation of ...
López Arribillaga, Erika (Date of defense: 2016-06-17)
Wnt/β-catenin and Notch signalling cooperate in regulating the transcription of various genes specifically in the small intestinal stem and progenitor cell compartments. We characterized Bmi1 functionally in this context ...
José Segarra-Martínez, Anabel (Date of defense: 2011-12-13)
Els tractaments actuals pel càncer de pàncreas presenten un eficàcia limitada de manera que es necessari el desenvolupament de noves teràpies antitumorals. La teràpia gènica pel càncer de pàncreas basada en l’ús d’adenovirus ...
Lotinac, Damir (Date of defense: 2017-12-14)
Classical planning is the problem of finding a sequence of actions, from a given initial state to some goal state. While, in generalized planning, a plan is a solution to a set of planning problems, which belong to the ...
Solís Moruno, Manuel (Date of defense: 2021-09-14)
Autoinflammatory diseases are caused by an antigen independent hyperactivation of inflammatory pathways. The first genetic defect linked to an autoinflammatory disease was described almost 25 years ago and, since then, the ...
Saravia Santos, Rocio (Date of defense: 2019-01-10)
Cigarette smoking continues to be leading cause of preventable cause of death worldwide. Cognitive modulation by nicotine seems to be a key factor in nicotine addiction. Several studies indicate that initial nicotine intake ...
Mas Martín, Glòria (Date of defense: 2007-07-20)
En la levadura S. cerevisiae, un incremento de la osmolaridad extracelular activa la vía de Hog1, lo que produce una compleja respuesta adaptativa. Entre las respuestas adaptativas que Hog1 coordina, está un importante ...
Mansouri, Leila (Date of defense: 2023-03-27)
El continuo aumento de los proyectos de producción de datos genómicos a gran escala, como el "Earth BioGenome Project" (Lewin et al., 2018), pone los métodos de análisis de datos bajo una presión sin precedentes. Es necesario ...
Vázquez Oliver, Anna (Date of defense: 2022-02-18)
Intellectual disability is a term used to describe a group of neurodevelopmental disorders defined by deficits in cognitive and adaptive functioning with onset during the developmental period. Preclinical research suggest ...
Cornet Bartolomé, Carles (Date of defense: 2020-01-17)
High drug attrition rate during clinical and post market phases is one of the major factors contributing to the pharmaceutical industry productivity crisis. This problem is especially worrisome in the cancer field, where ...
Higuera González, Laura (Date of defense: 2021-10-01)
Macrophages play crucial roles in the defense of the organism against a wide range of pathogens. Macrophages can rapidly adapt to perturbations in the microenvironment due to the existence of a network of transcription ...
Sebastián Perez, Rubén (Date of defense: 2021-09-10)
Chromocenters are established after the 2-cell (2C) stage during mouse embryonic development, but the factors that mediate chromocenter formation remain largely unknown. To identify regulators of 2C heterochromatin ...
Salat Canela, Clàudia (Date of defense: 2020-09-30)
Living organisms must respond to changes in their environment in order to overcome stress situations. In Schizosaccharomyces pombe, Sty1 MAP kinase is required to survive to a wide range of environmental stresses. The main ...
Di Vona, Chiara (Date of defense: 2013-09-20)
The view on how protein kinases regulate gene expression have recently expanded to include not only transcription factors but also histones, chromatin remodelers or components of the basal transcription machinery, which ...
Pohl, Andy (Date of defense: 2014-10-03)
Genome-wide analysis of the nucleosome positioning and histone H1 isoform content of the T47D breast cancer cell line has found a number of observations, namely that with a gentle digestion of microccocal nuclease (MNase), ...