Mostrando ítems 31-40 de 94
Iannone, Camilla (Fecha de defensa: 2014-05-23)
Intron removal is a necessary step for expression of most genes in higher eukaryotes, and alternative splice selection is a highly regulated mechanism that endows a single gene with the possibility to ...
Benisty, Hannah (Fecha de defensa: 2019-12-13)
The RAS oncogenes KRAS, NRAS and HRAS are mutated in one third of human cancers where they exhibit different mutation patterns. A potential factor contributing to this mutation bias is the variation ...
García Santamarina, Sarela (Fecha de defensa: 2013-06-14)
Oxidation of specific cysteines in proteins by hydrogen peroxide (H2O2) is a cellular mechanism that triggers signalling pathways, such as the antioxidant responses in microbial systems. However, H2O2 ...
Padró i Jové, Mercè (Fecha de defensa: 2011-03-28)
Alterations in the expression of carbohydrates and the enzymes involved in their synthesis (glycosidases and glycosyltransferases) can be considered as universal feature of malignant transformation. ...
Viñas Castells, Rosa (Fecha de defensa: 2013-05-24)
Epithelial to mesenchymal transition (EMT) is a process by which epithelial cells acquire a mesenchymal phenotype. It is characterized by the down-regulation of the adherens junction protein E-cadherin, ...
Fornés Crespo, Oriol (Fecha de defensa: 2015-01-21)
Protein-DNA interactions are indispensable players in the daily activities of cells. DNA-binding proteins regulate gene expression and are responsible of DNA replication, packaging, repair and recombination. ...
Çavusoglu, Kader (Fecha de defensa: 2013-06-07)
This project was carried out in the Cell Signaling Research Group headed by Dr. Carme Caelles at IRB Barcelona. As a part of the research-line that deals with physiological and pharmacological ...
Battola, Andrea (Fecha de defensa: 2017-12-12)
Problemes en la replicació de l’ADN, condensació o de-catenació generen ponts anafàsics al punt de divisió, que en molts casos provoquen inestabilitat genòmica. La cèl·lula respon a aquest problema ...
Jiménez-Castells, Carmen (Fecha de defensa: 2010-12-20)
Carbohydrate-binding proteins of non-immunological origin -lectins- have been recognized over the last decades as decisive players in numerous biological processes, ranging from cellcell communication, ...
Martínez Høyer, Sergio (Fecha de defensa: 2012-10-11)
The calcineurin-NFATc signaling pathway is involved in many aspects of the development and function of the immune, neural, skeletal, cardiovascular and muscular system of vertebrates. Regulators ...