Universitat Pompeu Fabra: Recent submissions
Now showing items 281-300 of 3325
Descolonizando el Gadir fenicio: Convivencia y multiculturalidad en la Bahía de Cádiz (siglos IX-VI a.n.e.)
Colonia, colonialismo o colonización son términos y conceptos muy recurrentes en las reconstrucciones históricoarqueológicas del pasado. Los movimientos migratorios que se desarrollaron en el Mediterráneo y Atlántico ...
Complexity changes in neuroimaging signals point to mechanisms of neuropsychiatric disease
The past decade has seen several attempts to employ the entropy of neuroimaging signals as a potential biomarker for cognitive decline or traumatic brain injury (C. Y. Liu et al. 2013; Adhikari et al. 2017; Li et al. 2018). ...
The calculation of damages in EU intellectual property law: an assessment of the harmonisation approach used in article 13(1) of Directive 2004/48/EC on the enforcement of IPRs
The claim for compensation is a key tool in any legal system. Due to their ubiquitous nature, the calculation of damages for the infringement of intellectual property rights exhibits significant peculiarities. In its ...
US Latina/o/x migrations, translations and routes of reception: an integrated critique
The object of study of this thesis is a special case of translation: the Anglophone literature of writers of Caribbean or Latin American origin in the United States translated into Spanish. This case is special because of ...
The effect of foreign language on emotion regulation
Hay personas que se pueden enfrentar, por unas razones u otras, a un tratamiento terapéutico en un idioma que no es su idioma nativo. Hasta la fecha, no hay apenas información de qué efecto tendría usar una lengua no nativa ...
Towards a statistical physics of major evolutionary transitions: information, thermodynamics and ecology at the mathematical foundations of evolution
This thesis aims at establishing the basis for a statistical physics theory of major evolutionary transitions. Its structure is based on three major pillars: nonequilibrium thermodynamics and information theory, stochastic ...
Essays in safe assets: trends, drivers and implications for financial stability
This dissertation consists of three chapters centred on safe assets, shedding light on different aspects of the growing literature on the subject. Chapter 1 introduces the set of assets that falls under the safe category, ...
Essays in time series econometrics
This doctoral thesis develops new methods for time series analysis and applies these to prominent empirical problems in macroeconomics. It contains three chapters. Chapter one proposes a new non-parametric generalized method ...
Unveiling the role of Her9/Notch pathway in the maintenance of stemness in the hindbrain boundaries
The generation of cell diversity in the embryonic brain relies on the balance between cell proliferation and differentiation. The hindbrain boundary cells specify at the interface between adjacent compartments. Boundary ...
Super-resolution imaging uncovers key temporal changes in chromatin structure and pluripotent gene reactivation in single reprogramming cells
Elucidating the mechanism of somatic cell reprogramming has been hampered by the limitations of iPSC systems to uncover the correctly reprogramming cells. Here, by using the highly efficient heterokaryon system we dissected ...
Advanced microscopy to resolve the higher-order organization of the exocyst
The exocyst is an heterooctameric protein complex that tethers secretory vesicles to the plasma membrane during exocytosis. Each exocytic event is mediated by 10-15 exocysts. However, how multiple exocysts organize in time ...
Essays on the credit market and macroeconomic policy
This dissertation consists of three essays. In the first chapter, using a series of identified monetary policy shocks for Peru, I show robust evidence of supply side mechanisms of monetary policy for the credit market ...
Transcriptomic determinants of vertebrate photoreceptors and other sensory cells
The nervous system comprises an immense number of cells that serve highly specialized roles. Accordingly, they possess unique morphological and functional attributes, greatly shaped by specific Alternative Splicing (AS) ...
Investigating sperm RNA dynamics in intergenerational inheritance using nanopore sequencing
The aim of this thesis is to delve into sperm RNA dynamics during maturation and paternal inheritance. To obtain an integrative multi-omics view of sperm RNA during these processes, I turned to the new direct RNA sequencing ...
Precariedad laboral, estrés crónico y salud mental: un estudio sobre el entorno psicosocial laboral como posible mecanismo causal
El objetivo principal de esta tesis fue analizar el posible papel mediador del entorno psicosocial del trabajo en la relación entre la precariedad laboral, la salud mental y el estrés crónico. Se combinaron diferentes ...
Conservation through the lens of population genomics: the case of Cuvier's gazelles and western gorillas
The field of genomics can be used to help in threatened species conservation by guiding conservation efforts. In this thesis we have studied Cuvier’s gazelles to compare the genetic diversity and inbreeding between the ...
Computational analysis of ribonucleoprotein networks
Ribonucleoprotein condensates such as stress granules (SGs) and processing bodies (PBs) form in response to specific stimuli in the cell. Even though the key protein and RNA elements of these condensates are starting to ...
Evolutionary insights into primate gene regulation and development of methods to study DNA modifications
Changes in the epigenetic regulation of gene expression have important implications for evolution. However, the study of these changes (i) has not been consistently assessed across closely related species, (ii) oftentimes ...
An in silico clinical trial platform based on systems biology approaches
El procés de descobriment i desenvolupament de fàrmacs (DDD) és costós tant econòmic com temporalment, i el qual resulta en nivells d'èxit molt reduïts. Una gran quantitat de compostos son analitzats i molts descartats en ...
Engram pathology in Down syndrome: molecular and cellular mechanisms
Down syndrome (DS) is the most common genetic form of intellectual disability and arises from the partial or total trisomy of the Homo Sapiens Autosome 21. The cellular and molecular mechanisms that contribute to memory ...
