Atlas-based segmentation of multiple sclerosis lesions in magnetic resonance imaging 

    Cabezas Grebol, Mariano (Date of defense: 2013-07-16)

    This thesis deals with the segmentation of brain magnetic resonance imaging applied to multiple sclerosis patients. This disease is characterised by the presence of white matter lesions in this image modality. After a ...

    Automated brain structure segmentation in magnetic resonance images of multiple sclerosis patients 

    González-Villà, Sandra (Date of defense: 2019-05-31)

    This thesis is focused on the automated segmentation of the brain structures in magnetic resonance images, applied to multiple sclerosis patients. This disease is characterized by the presence of lesions, which affect the ...

    Automated brain tissue segmentation of magnetic resonance images in multiple sclerosis 

    Valverde Valverde, Sergi (Date of defense: 2016-06-14)

    L'objectiu principal d'aquesta tesi és el desenvolupament d'un nou mètode de segmentació totalment automàtic capaç de mesurar amb precisió el volum cerebral en imatges de pacients d'EM amb lesions. El mètode que hem proposat ...

    Automated methods on magnetic resonance brain imaging in multiple sclerosis 

    Roura Pérez, Eloy (Date of defense: 2016-07-01)

    In this thesis, we have focused on the image pre-processing in order to enhance the image information. The main aspects of this enhancement rely on removing any image noise and correcting any intensity bias induced by the ...

    Automatic segmentation of brain structures in magnetic resonance images using deep learning techniques 

    Kushibar, Kaisar (Date of defense: 2020-07-20)

    This PhD thesis focuses on the development of deep learning based methods for accurate segmentation of the sub-cortical brain structures from MRI. First, we have proposed a 2.5D CNN architecture that combines convolutional ...

    Avaluació de l'efecte d'una estimulació auditiva rítmica sobre els paràmetres de la marxa i equilibri en persones amb ictus 

    Gonzalez-Hoelling, Samira (Date of defense: 2024-03-18)

    Stroke is the leading cause of functional motor disorders in adults and, in most cases, alters gait patterns and balance when standing and walking. Rhythmic techniques are recommended to improve gait and balance, since ...

    Cognitive function in obesity: interactions with the gut microbiome 

    Arnoriaga Rodríguez, María (Date of defense: 2022-04-27)

    Obesity is considered a modifiable risk factor for cognitive impairment which, in turn, predisposes to overeating and weight gain. Compelling evidence in animal models has demonstrated the impact of the gut microbiome on ...

    Deep learning for atrophy quantification in brain magnetic resonance imaging 

    Bernal Moyano, Jose (Date of defense: 2020-10-27)

    The quantification of cerebral atrophy is fundamental in neuroinformatics since it permits diagnosing brain diseases, assessing their progression, and determining the effectiveness of novel treatments to counteract them. ...

    Deep learning methods for automated detection of new multiple sclerosis lesions in longitudinal magnetic resonance images 

    Salem, Mostafa (Date of defense: 2020-02-13)

    This thesis is focused on developing novel and fully automated methods for the detection of new multiple sclerosis (MS) lesions in longitudinal brain magnetic resonance imaging (MRI). First, we proposed a fully automated ...

    Deep learning methods for extraction of neuroimage markers in the prognosis of brain pathologies 

    Clèrigues Garcia, Albert (Date of defense: 2023-02-13)

    This PhD thesis focuses on improving the extraction of neuroimage markers for the prognosis and outcome prediction of neurological pathologies such as ischemic stroke, Alzheimer’s disease (AD) and multiple sclerosis (MS). ...

    Depresión, ansiedad y calidad de vida percibida en pacientes fumadores con ictus agudo 

    Maldonado Manzano, Eduard (Date of defense: 2020-07-27)

    Almost all people with stroke have vascular risk factors that influence the risk of developing this disease, many of which can be modified. The study included 115 smokers hospitalized at Dr. University Hospital. Josep ...

    Deterioro cognitivo leve y demencia tipo Alzheimer en personas con discapacidad intelectual: detección, clasificación y caracterización de la evolución clínica 

    Rodriguez-Hidalgo, Emili (Date of defense: 2023-12-22)

    Background. Intellectual disability is a neurodevelopment disorder affecting intellectual functioning and adaptive behavior. The increase of life expectancy of this population leads to an increase of mental health pathologies ...

    Determinació del patró de miRNA en líquid cefaloraquidi de pacients amb esclerosi múltiple (estudi miEM) 

    Ramió i Torrentà, Lluís (Date of defense: 2014-10-23)

    Multiple sclerosis is a chronic neurological disease of the central nervous system with unknown, autoimmune mechanism, and a progressive and disabling course. Lipid-specific oligoclonal IgM bands in cerebrospinal fluid ...

    Efecte de l'administració de l'rt-PA en condicions isquèmiques in vitro i in vivo: Cav-1 com a potencial biomarcador de volum d'infart 

    Comajoan von Arend, Pau (Date of defense: 2019-12-18)

    Recombinant tissue plasminogen activator (rt-PA) is currently the only FDA-approved drug for the treatment of acute ischaemic stroke. However, the application of this therapy is limited to <5-7% of patients due to the ...

    El meu fill té autisme, i ara què? Anàlisi de les necessitats de les famílies amb nens amb autisme durant el procés d’avaluació diagnòstica a Catalunya. Disseny d’un programa d’acollida i suport per a famílies 

    Montero Camacho, Mario Raul (Date of defense: 2018-05-18)

    A number of studies show that the prevalence of ASD is rising in alarming numbers, currently reaching 1 in every 68 people. The most effective approach 2/2 to improve the lives of these children is to support, train and ...

    Electrical stimulation of the medial forebrain bundle as a potential therapy for Alzheimer's disease: effects on molecular markers in rodent model 

    Puig Parnau, Irene (Date of defense: 2021-06-01)

    Electrical stimulation of deep brain areas has been suggested as a novel approach to restore memory circuits in Alzheimer’s disease (AD). Previous studies from our group have demonstrated that rewarding stimulation of the ...

    Esclerosi múltiple i brots: estrès, afrontament i curs de la malaltia 

    Fàbregas Casas, Laura (Date of defense: 2014-06-16)

    The effects of stress on the nervous system, the endocrine system and especially on the immune system have generated the hypothesis that it might be a relevant factor in the evolution of multiple sclerosis (MS). The exposure ...

    Estudi de la incidència del GPS en la qualitat de vida de les cuidadores i les persones amb malaltia d’Alzheimer 

    Ribas Miquel, Gloria (Date of defense: 2021-04-29)

    GPS is an invention that allows us to know the position for people with disorientation and track it in motion, making it easier to find them in case of loss. The study used a combined methodology quantitative and qualitative. ...

    Grape stalk and coffee polyphenolic extracts administration as new pharmacological strategies to modulate spinal cord injury-induced neuropathic pain in mice 

    Bagó Mas, Anna (Date of defense: 2022-03-18)

    More than half of spinal cord injury patients develop central neuropathic pain, which is largely refractory to current treatments. Developing neuropathic pain has a high impact on the quality of life becoming an emotional, ...

    Identificación de genes de susceptibilidad en esclerosis múltiple. Descripción clínica y análisis genético de una extensa familia de etnia gitana (Estudio EMGypsy) 

    Robles Cedeño, René (Date of defense: 2016-07-19)

    Multiple sclerosis is a chronic disease of the central nervous system which has an unknown aetiology and an autoimmune mechanism. Two pathogenic processes, inflammation and neurodegeneration, converge causing a progressive ...