Departament de Ciències Mèdiques

La Universitat de Girona té més de 15.000 estudiants i 1.400 professors. Ofereix uns 50 estudis de grau i més de 20 màsters. S’organitza en 9 centres docents, 1 Escola de Doctorat, 6 centres adscrits. L’activitat de recerca es du a terme en 24 departaments, 12 instituts de recerca i més de 40 càtedres, a més d’un centenar de grups de recerca especialitzat. Té la seu a la ciutat de Girona i s’integra en el sistema d’universitats públiques catalanes.

També trobareu les tesis recol·lectades al repositori DUGi .


Si sou doctor o doctora de la Universitat de Girona i voleu publicar la vostra tesi a TDX, contacteu amb tdx@udg.edu. Per a més informació consulteu les preguntes més freqüents.

Recent Submissions

El nivell i la variació del risc cardiovascular en la prevenció primària de la demència 

Fages Masmiquel, Ester (Date of defense: 2023-09-14)

Dementia causes progressive cognitive impairment and inability to lead an independent life. Currently, there is no curative treatment for it, and thus primary prevention is essential. Age is the main risk factor for ...

Predicción del riesgo cardiovascular en población de 75 o más años del Mediterráneo 

Guzmán Heras, Lidia Elizabeth (Date of defense: 2023-07-05)

The increase of elderly population in Spain is one of the most important challenges for their caregivers, healthcare professionals, and the society in general. The elderly population has the highest incidence rate of ...

Relació de la proteïna C-reactiva, el quocient neutròfils/limfòcits i l’adiponectina d’alt pes molecular amb paràmetres d’obesitat i de risc cardiometabòlic en nens prepuberals sans. Efecte modulador dels estils de vida 

Díaz Roldán, Ferran (Date of defense: 2023-07-03)

Childhood obesity is one of the most important public health problems and is associated with cardiometabolic risk factors (CMR). Low-grade inflammation plays a prominent role in the development of cardiometabolic alterations ...

Posible rol de las neuregulinas en la fisiología del tejido adiposo en asociación con obesidad y diabetes mellitus tipo 2 

Martínez Merchan, Cristina (Date of defense: 2023-06-28)

Different studies link the metabolic alterations of obesity with imbalances in neuregulin 4 levels. In this study we hypothesize that signaling of neuregulin isoforms (NRG) produced through ERBB receptors in human adipose ...

Methylome profiling of B and T cells along multiple sclerosis disease progression: a pilot study 

Celarain Sanz, Naiara (Date of defense: 2023-06-26)

Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune and neurodegenerative disease characterized by the infiltration of autoreactive immune cells into the central nervous system that leads to axonal damage, ...

L’extracte de fulla d’olivera redueix la pressió arterial de pacients amb hipertensió arterial lleugera sense malaltia vascular subclínica 

Espín Sánchez, Rufina (Date of defense: 2023-06-16)

Introduction: Hypertension is the common cardiovascular risk factor and affects 20 to 50% of the population. Treatment, with drugs or not, involves improving lifestyle. Olive leaf extract has traditionally been taken to ...

Study of two analogues of pituitary adenylate cyclase-activating polypeptide as novel therapeutic compounds for Huntington’s disease 

Solés Tarrés, Irene (Date of defense: 2023-06-14)

Huntington’s disease (HD) is a neurodegenerative genetic disorder with no effective treatment characterized by motor discoordination, deficits in cognitive function (acquiring new knowledges, memory, understanding…), and ...

Estudi de l’alliberació del calci intracel·lular en cardiomiòcits derivats de iPSC de pacients amb taquicàrdia ventricular polimòrfica catecolaminèrgica (CPVT) 

Carreras Gorgals, David (Date of defense: 2023-05-30)

In a small region of the island of Gran Canaria, 11 cases of sudden cardiac death (SCD) were registered in emotional or physical stress situations in young individuals between 1994 and 2007 in four seemingly unrelated ...

New approaches for the study and treatment of aggressive cancers 

Polonio Alcalá, Emma (Date of defense: 2023-05-17)

Although there are therapies for triple negative breast cancer (TNBC) and epidermal growth factor-mutated non-small cell lung cancer (EGFRm NSCLC), these two subtypes of cancer are very aggressive, and most patients develop ...

Estudio de la regulación génica en el locus SCN5A-SCN10A y su implicación en la etiología del Síndrome de Brugada 

Pérez Agustín, Adrián (Date of defense: 2023-03-28)

Brugada syndrome (SBr) is a cardiac electrical disease associated with a high susceptibility to ventricular arrhythmias and sudden cardiac death. Genetic variants in the coding regions of the SCN5A gene, which encodes for ...

Clinical epidemiology and molecular biology of cutaneous and mucosal melanoma in Girona 1994-2018 

Carbó Bagué, Anna (Date of defense: 2023-03-27)

In this doctoral thesis, the epidemiology of cutaneous and mucosal melanoma is analyzed, as well as its molecular profile to provide new knowledge on a population basis in the province of Girona. The cancer registry of ...

Nova metodologia d’anàlisi de distribucions de dosi per algorismes de càlcul de dosi absorbida en radioteràpia externa que simulen el transport de radiació en medi 

Jurado Bruggeman, Diego (Date of defense: 2023-03-16)

Introduction Different types of dose calculation algorithms for external beam radiation therapy with MV photons coexist nowadays. The oldest ones are convolution/superposition (C/S), which consider all media as water of ...

Dehiscencia de anastomosis en la cirugía del cáncer de recto: incidencia, factores pronósticos y morbimortalidad asociada 

Farrés Coll, Ramon (Date of defense: 2023-03-10)

Introduction: Anastomotic leak (AL) is the most feared complication in the postoperative period for patients with rectal cancer. Objectives: To determine the real rate of AL in patients operated on for rectal cancer. ...

Factors pronòstics en la dehiscència anastomòtica de la cirurgia del càncer de còlon. Models de predicció actuals i validació externa independent 

Pigem Rodeja, Anna (Date of defense: 2023-03-03)

INTRODUCTION: Anastomotic leak (AL) is the most dreadful and life-threatening complication in colon cancer (CC) surgery. It is associated to an increase of morbimortality, longer hospital stay, increased healthcare costs ...

Molecular insights on arrhythmogenic cardiomyopathy: assessment of premature termination codons in desmosomal genes and variants reclassification 

Vallverdú Prats, Marta (Date of defense: 2023-02-03)

Arrhythmogenic cardiomyopathy (ACM) is an entity that groups different clinical forms of hereditable cardiac diseases that are associated to ventricular arrhythmia and sudden cardiac death. The main cases are characterized ...

Caracterización de polimorfismos genéticos implicados con el metabolismo de la citarabina y asociación con la respuesta y toxicidad a la quimioterapia en pacientes con leucemia mieloide aguda de riesgo intermedio 

Díaz Santa, Johana Alejandra (Date of defense: 2022-12-16)

Acute myeloid leukemia (AML) is adults' most common acute leukemia. Prognostic factors influencing treatment response and patient survival are diverse, the most relevant being those associated with specific cytogenetic and ...

Estudio del impacto de UGT2B17 y PD-1 en el trasplante alogénico de progenitores hematopoyéticos a partir de donante emparentado HLA idéntico 

Santos Carvajal, Nazly (Date of defense: 2022-11-25)

Study of the impact of UGT2B17 and PD-1 on allogeneic transplantation of hematopoietic progenitors (allo-TPH) from HLA-identical related donor. everal genetic factors can favor the development of graft-versus-host disease ...

Identificación y caracterización de factores de transcripción implicados en la regulación de procesos moleculares y cerebroreparadores en el ictus 

Camós Badia, Susanna (Date of defense: 2015-03-27)

The aim of this thesis was to identify transcriptional regulators involved in the modulation of ischaemia, as well as brain plasticity processes responsible for compensating the ischaemic lesions, in order to establish the ...

Reinterpretació de les variants genètiques identificades en una unitat especialitzada en cardiopaties familiars 

Fernandez Falgueras, Anna (Date of defense: 2022-12-13)

Sudden cardiac death (SCD) is defined as a natural and unexpected death due to cardiac etiology. In addition, when the cause of death remains unexplained after a complete autopsy, a cardiac arrhythmia is suspected as a ...

Valoració dels canvis que pateix la uretra durant l’embaràs objectivats per ecografia 2D i la relació d’aquests amb l’aparició d’incontinència d’orina en la gestació 

Carrera Boix, Alícia (Date of defense: 2022-11-04)

Urinary incontinence (UI) is a dysfunction that has a very negative impact on the quality of life of women who suffer from it (low self-esteem, shame, restriction of social contacts, etc.). Different factors involved in ...

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